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MMTV-WNT1 xenograft tumor model

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123334

    Porcupine Wnt Cancer
    GNF-1331 (compound 19) is a potent, selective and orally bioavailable porcupine inhibitor (IC50=12 nM). GNF-1331 blocks Wnt ligand secretion and subsequent Wnt signaling activity, and induces significant antitumor effects in the mouse MMTV-WNT1 xenograft tumor model .
    GNF-1331

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