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Results for "

MRP4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fluorescent Dye (1) Leukotriene Receptor (2) LPL Receptor (4) OAT (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Inflammation/Immunology (4) Metabolic Disease (2)

8

Inhibitors & Agonists

1

Natural
Products

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Ceefourin 1	Others	Cancer
Ceefourin 1 is a potent and highly selective multidrug resistance protein 4 (MRP4) inhibitor. Ceefourin 1 inhibits transport of a broad range of MRP4 substrates, yet is highly selective for MRP4 over other ABC transporters. Ceefourin 1 is a benzothiazol and primarily as a chemosensitizer for high-risk neuroblastoma .

PU 23	Others	Cancer
PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine .

MK-571 sodium Maximum Cited Publications 24 Publications Verification L-660711 sodium	Leukotriene Receptor LPL Receptor	Inflammation/Immunology
MK-571 (L-660711) sodium is an orally active, potent and selective competitive *leukotriene D₄ (LTD₄)* receptor antagonist, with K_i values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of multidrug resistance-associated protein MRP4 (ABCC4)** and ABCC1 (MRP1). MK-571 sodium inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release .

BMS-986020 sodium 5+ Cited Publications AM152 sodium	LPL Receptor	Metabolic Disease Inflammation/Immunology
BMS-986020 (AM152) sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist . BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC₅₀s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively . BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF) .

BMS-986020 5+ Cited Publications AM152	LPL Receptor	Metabolic Disease Inflammation/Immunology
BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist . BMS-986020 inhibits bile acid and phospholipid transporters with IC₅₀s of 4.8 µM, 6.2 µM, and 7.5 µM for BSEP, MRP4, and MDR3, respectively . BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF) .

MK-571 Maximum Cited Publications 24 Publications Verification L-660711	Leukotriene Receptor LPL Receptor	Inflammation/Immunology
MK-571 (L-660711) is an orally active, potent and selective competitive *leukotriene D₄ (LTD₄)* receptor antagonist, with K_i values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 is also a MRP4** and ABCC1 (MRP1) inhibitor. MK-571 inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release .

Indican Indoxyl-β-D-glucoside	Fluorescent Dye OAT	Others
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .

Ceefourin 2	Others	Cardiovascular Disease Others
Ceefourin 2 is a potent and highly selective inhibitor of *MRP4. Ceefourin 2 inhibits the transport of MRP4* substrates but is not selective for other ABC transporters. Ceefourin 2 shows lower cytotoxicity and higher microsomal and acid stability .

Cat. No.	Compare	Product Name	Application	Reactivity

	MRP4 Antibody (YA1166) MRP4; MOATB; MOAT-B; EST170205	IHC-P	Human
	MRP4 Antibody (YA1166) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1166), targeting MRP4. MRP4 Antibody (YA1166) can be used for IHC-P experiment in human background.

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