P. gingivalis

By Targets:	Antibiotic (1) Bacterial (3) MyD88 (1) Parasite (1) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (1) Infection (3) Inflammation/Immunology (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2906

Limonianin Atalantoflavone	Parasite	Cancer
Limonianin (Atalantoflavone) is a flavone, that can be isolated from Erythrina sigmoidea and the root bark of Citrus limonia. Limonianin presents inhibitory effect against P. gingivalis. Limonianin shows cytotoxic activity against multidrug-resistant (MDR) cancer cell lines .

HY-30263

4-Heptyloxyphenol p-(Heptyloxy)phenol	Bacterial	Infection
4-Heptyloxyphenol (p-(heptyloxy)phenol) has antibacterial activity agaisnt P. gingivalis, S. artemidis, Str. sobrinus (MIC: 0.10, 0.21, 0.14 mM) .

HY-D1056D

Lipopolysaccharides, from P. gingivalis LPS, from Porphyromonas gingivalis	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides are lipopolysaccharide endotoxins and TLR-4 activators that activate pathogenicity-associated molecular patterns (PAMPs) of the immune system and induce cell secretion of migrasomes. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and are composed of an antigenic O-specific chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from P. gingivalis is a kind of endotoxins derived from P. gingivalis .

HY-P4301

Di-aspartic acid	Bacterial	Infection
Di-aspartic acid (Aspartylaspartate) can be utilized as growth substrate for P. gingivalis, P. intermedia, P. nigrescens and F. nucleatum .

HY-164173

LPS-PG	Toll-like Receptor (TLR) MyD88	Inflammation/Immunology
LPS-PG is a lipopolysaccharide from Porphyromonas gingivalis (P. gingivalis). LPS-PG is an important virulence factor in the pathogenesis of periodontal disease and activates immune cells via Toll-like receptor 2 (TLR2), rather than the receptor for Escherichia coli (E. coli), Toll-like receptor 4 (TLR4). A lipoprotein from LPS-PG has been shown to be the major component responsible for TLR2-mediated cell activation .

HY-P2312

Human β-defensin-3 HβD-3	Antibiotic Bacterial	Infection
Human β-defensin-3 (HβD-3) is an antibiotic anti-microbial peptide produced by epithelial cells with antimicrobial activities and reduces the effect of inflammatory cytokine responses. Human β-defensin-3 is against different microbes with IC₉₀ values of 6-25 μg/ml .

Cat. No.	Product Name	Type

HY-D1056D

Lipopolysaccharides, from P. gingivalis LPS, from Porphyromonas gingivalis	Carbohydrates
Lipopolysaccharides are lipopolysaccharide endotoxins and TLR-4 activators that activate pathogenicity-associated molecular patterns (PAMPs) of the immune system and induce cell secretion of migrasomes. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and are composed of an antigenic O-specific chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from P. gingivalis is a kind of endotoxins derived from P. gingivalis .

Lipopolysaccharides, from P. gingivalis

LPS, from Porphyromonas gingivalis

Carbohydrates

Lipopolysaccharides are lipopolysaccharide endotoxins and TLR-4 activators that activate pathogenicity-associated molecular patterns (PAMPs) of the immune system and induce cell secretion of migrasomes. Lipopolysaccharides can be extracted from the outer leaflet of the outer membrane of Gram-negative bacteria and are composed of an antigenic O-specific chain, a core oligosaccharide, and lipid A. Lipopolysaccharides, from P. gingivalis is a kind of endotoxins derived from P. gingivalis .

Cat. No.	Product Name	Target	Research Area

HY-P4301

Di-aspartic acid	Bacterial	Infection
Di-aspartic acid (Aspartylaspartate) can be utilized as growth substrate for P. gingivalis, P. intermedia, P. nigrescens and F. nucleatum .

HY-P2312

Human β-defensin-3 HβD-3	Antibiotic Bacterial	Infection
Human β-defensin-3 (HβD-3) is an antibiotic anti-microbial peptide produced by epithelial cells with antimicrobial activities and reduces the effect of inflammatory cytokine responses. Human β-defensin-3 is against different microbes with IC₉₀ values of 6-25 μg/ml .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2906

Limonianin Atalantoflavone	Structural Classification Flavonoids Flavones Source classification Rutaceae Atalantia buxifolia (Poir.) Oliv. Plants	Parasite
Limonianin (Atalantoflavone) is a flavone, that can be isolated from Erythrina sigmoidea and the root bark of Citrus limonia. Limonianin presents inhibitory effect against P. gingivalis. Limonianin shows cytotoxic activity against multidrug-resistant (MDR) cancer cell lines .

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