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Results for "

RRM2

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Recombinant Proteins

1

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112358
    GW8510

    		CDK Neurological Disease Cancer
    GW8510 is a potent cyclin-dependent kinase-2 (CDK2) inhibitor. GW8510 is also a ribonucleotide reductase M2 (RRM2) inhibitor. GW8510 exhibits neuroprotective and anticancer activities [2] .
    GW8510
  • HY-B2116
    Osalmid

    Oxaphenamide; 4'-Hydroxysalicylanilide

    		 HBV Infection
    Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 μM.
    Osalmid
  • HY-153736
    NSC 194308

    		Others Cancer
    NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations .
    NSC 194308
  • HY-153898
    rTRD01

    		Others Neurological Disease
    rTRD01 is a TDP-43 ligand that binds to TDP-43’s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102–269). rTRD01 partially disrupts TDP-43’s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases .
    rTRD01
  • HY-RS12286
    RRM2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RRM2 Human Pre-designed siRNA Set A contains three designed siRNAs for RRM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RRM2 Human Pre-designed siRNA Set A
    RRM2 Human Pre-designed siRNA Set A
  • HY-RS12287
    RRM2B Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RRM2B Human Pre-designed siRNA Set A contains three designed siRNAs for RRM2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RRM2B Human Pre-designed siRNA Set A
    RRM2B Human Pre-designed siRNA Set A

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