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SHP2-IN-31

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164427
    SHP2-IN-31

    		SHP2 ERK Cancer
    SHP2-IN-31 is a SHP2 inhibitor, with IC50s of 13 nM (Wild-type SHP2), >10000 nM (SHP1), >10000 nM (SHP2 E76K) . SHP2-IN-31 inhibits pERK in a panel of tumor cells. SHP2-IN-31 inhibits tumor growth in RTK/KRAS-driven xenograft models .
    SHP2-IN-31

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