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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
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SNU-C4 3xFLAG-PXR KI cells

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169279
    PROTAC SMARCA2/4-degrader-34

    		Epigenetic Reader Domain PROTACs Cancer
    PROTAC SMARCA2/4-degrader-34 (compound 38) is a potent is a potent SMARCA2 and SMARCA4 PROTAC degrader. PROTAC SMARCA2/4-degrader-34 shows PXR binding affinity with DC50 value of 85.1 nM. PROTAC SMARCA2/4-degrader-34 decreases the protein expression of 3xFLAG-PXR. (Pink: Ligand for target protein (HY-169280); Black: Linker (HY-43048); Blue: Ligand for E3 ligase (HY-125845) .
    PROTAC SMARCA2/4-degrader-34

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