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Salvia miltiorrhiza

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (2) Apoptosis (1) Autophagy (6) Bacterial (2) Caspase (1) GABA Receptor (1) NF-κB (1) NO Synthase (1) SARS-CoV (4) STAT (2) VEGFR (2) Virus Protease (2)
By Research Areas:	Cancer (11) Cardiovascular Disease (9) Infection (2) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (2)

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Natural
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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-119720

Neocryptotanshinone	NF-κB NO Synthase	Inflammation/Immunology
Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways .

HY-N1179

Tanshinone IIB	Apoptosis	Cardiovascular Disease Neurological Disease
Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis .

HY-N3201

Neoprzewaquinone A	Others	Others
Neoprzewaquinone A is isolated from the roots of Salvia miltiorrhiza .

HY-N7522

Salvianolic acid E	Others	Others
Salvianolic acid E is a natural compound isolated from Salvia miltiorrhiza .

HY-N0320

Salvianolic acid D	Others	Cardiovascular Disease
Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .

HY-N1951

Miltirone	GABA Receptor	Neurological Disease
Miltirone is a natural compound present in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC₅₀ of 0.3 μM .

HY-B0923

Danthron 1 Publications Verification Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone	AMPK Autophagy Bacterial Virus Protease	Cancer
Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.

HY-120451

Salvinone	Others	Inflammation/Immunology
Salvinone (Compound 49) is a compound that can be isolated from Salvia miltiorrhiza .

HY-N1180

Tanshinlactone	SARS-CoV	Infection
Tanshinlactone is a seco-abietanoid that can be isolated from Salvia miltiorrhiza. Tanshinlactone is a coronavirus (CoV) inhibitor. Tanshinlactone modulates interleukin-2 and interferon-γ gene expression .

HY-123080

Tanshinol B	Others	Others
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .

HY-N0174

Cryptotanshinone Maximum Cited Publications 35 Publications Verification Cryptotanshinon; Tanshinone c	STAT Autophagy	Cancer
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC₅₀ of 4.6 μM.

HY-125847

Salvianolic acid F	Others	Cancer
Salvianolic acid F is a kind of Salvianolic Acids. Salvianolic Acids is the most effective and abundant compounds extracted from Salvia miltiorrhiza, with good anti-oxidative activity .

HY-N8617

Trijuganone C	Caspase	Cancer
Trijuganone C, a natural product extracted from Salvia miltiorrhiza, inhibits the proliferation of cancer cells through induction of apoptosis mediated by mitochondrial dysfunction and caspase activation .

HY-126416

Methyl tanshinonate	SARS-CoV	Infection Metabolic Disease
Methyl tanshinonate is a tanshinone, that can be isolated from Salvia miltiorrhiza (S. miltiorrhiza) Bunge (Lamiaceae). Methyl tanshinonate is a potent inhibitor of M ^pro enzyme in SARS-CoV (IC₅₀ = 21.1 µM). Methyl tanshinonate can be used for diabetes and SARS-CoV research .

HY-N7761

Trijuganone B Tetrahydro tanshinone I	Others	Cancer
Trijuganone B (Tetrahydro tanshinone I) can be extracted from from the roots of Salvia miltiorrhiza f. alba. Trijuganone B inhibits the proliferation of leukemia cells .

HY-N1362

Salvianolic acid B 5+ Cited Publications Lithospermic acid B	Autophagy	Cardiovascular Disease
Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.

HY-N0135

Tanshinone IIA 10+ Cited Publications Dan Shen ketone	VEGFR	Cardiovascular Disease Cancer
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-N0320R

Salvianolic acid D (Standard)	Others	Cardiovascular Disease
Salvianolic acid D (Standard) is the analytical standard of Salvianolic acid D. This product is intended for research and analytical applications. Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .

HY-N0360

Dihydrotanshinone I 4 Publications Verification	SARS-CoV	Cardiovascular Disease
Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.

HY-N0823

Lithospermic acid (+)-Lithospermic acid	Others	Inflammation/Immunology
Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl₄)-induced acute liver damage in vitro and in vivo .

HY-B0923R

Danthron (Standard)	AMPK Autophagy Bacterial Virus Protease	Cancer
Danthron (Standard) is the analytical standard of Danthron. This product is intended for research and analytical applications. Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.

HY-N0174R

Cryptotanshinone (Standard)	STAT Autophagy	Cancer
Cryptotanshinone (Standard) is the analytical standard of Cryptotanshinone. This product is intended for research and analytical applications. Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC₅₀ of 4.6 μM.

HY-N0135R

Tanshinone IIA (Standard)	VEGFR	Cardiovascular Disease Cancer
Tanshinone IIA (Standard) is the analytical standard of Tanshinone IIA. This product is intended for research and analytical applications. Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

HY-N1362R

Salvianolic acid B (Standard)	Autophagy	Cardiovascular Disease
Salvianolic acid B (Standard) is the analytical standard of Salvianolic acid B. This product is intended for research and analytical applications. Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.

HY-N0360R

Dihydrotanshinone I (Standard)	SARS-CoV	Cardiovascular Disease
Dihydrotanshinone I (Standard) is the analytical standard of Dihydrotanshinone I. This product is intended for research and analytical applications. Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge which has been widely used for treating cardiovascular diseases. Dihydrotanshinone I exhibits entry-blocking effect for MERS-CoV.

HY-N0823R

Lithospermic acid (Standard)	Others	Inflammation/Immunology
Lithospermic acid (Standard) is the analytical standard of Lithospermic acid. This product is intended for research and analytical applications. Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo .

HY-N10800

1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione	Others	Cancer
1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione is a kind of chemical constituents of Salvia miltiorrhiza f. alba. The dihydroisotanshinone with a para-quinone moiety shows cytotoxicity and anti-tumor activity .

HY-N10922

(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone	Others	Cancer
(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a Palmitate, can be isolated from the root tissue of Salvia miltiorrhiza. (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3) shows anti-cancer activity against human cancer cell lines with DC₅₀s of 25.5 μg/mL (HeLa), 37.5 μg/mL (HepG2), 30.2 μg/mL (OVCAR-3), respectively .

Neocryptotanshinone	Quinones Structural Classification Classification of Application Fields Terpenoids Labiatae Source classification Samanea saman (Jacq.) Merr. Diterpenoids Plants Naphthalene Quinones Inflammation/Immunology Disease Research Fields	NF-κB NO Synthase
Neocryptotanshinone, a fatty diterpenoids from Salvia Miltiorrhiza, inhibits lipopolysaccharide-induced inflammation by suppression of NF-κB and iNOS signaling pathways .

Tanshinone IIB	Cardiovascular Disease Structural Classification Natural Products Neurological Disease Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Source classification Plants Disease Research Fields	Apoptosis
Tanshinone IIB is a major active constituent of the roots of Salvia miltiorrhiza (Danshen) widely used for the research of stroke and coronary heart disease in Asian countries. Tanshinone IIB has a neuroprotective effect via inhibition of apoptosis .

Neoprzewaquinone A	Classification of Application Fields Terpenoids Labiatae Source classification Samanea saman (Jacq.) Merr. Other Diseases Diterpenoids Plants Disease Research Fields	Others
Neoprzewaquinone A is isolated from the roots of Salvia miltiorrhiza .

Salvianolic acid E	Stilbenes Classification of Application Fields Labiatae Source classification Samanea saman (Jacq.) Merr. Other Diseases Other Phenylpropanoids Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields	Others
Salvianolic acid E is a natural compound isolated from Salvia miltiorrhiza .

Salvianolic acid D	Cardiovascular Disease Structural Classification Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields	Others
Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .

Miltirone	Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Source classification Diterpenoids Plants	GABA Receptor
Miltirone is a natural compound present in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC₅₀ of 0.3 μM .

Danthron 1 Publications Verification Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone	Quinones Structural Classification Classification of Application Fields Anthraquinones Labiatae Samanea saman (Jacq.) Merr. Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	AMPK Autophagy Bacterial Virus Protease
Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.

Salvinone	Structural Classification Monophenols Labiatae Samanea saman (Jacq.) Merr. Source classification Phenols Plants	Others
Salvinone (Compound 49) is a compound that can be isolated from Salvia miltiorrhiza .

Tanshinlactone	Structural Classification Terpenoids Labiatae Samanea saman (Jacq.) Merr. Source classification Diterpenoids Plants	SARS-CoV
Tanshinlactone is a seco-abietanoid that can be isolated from Salvia miltiorrhiza. Tanshinlactone is a coronavirus (CoV) inhibitor. Tanshinlactone modulates interleukin-2 and interferon-γ gene expression .

Tanshinol B	Quinones Structural Classification Calea platylepis Labiatae Source classification Plants Naphthalene Quinones	Others
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .

Cryptotanshinone Maximum Cited Publications 35 Publications Verification Cryptotanshinon; Tanshinone c	Quinones Structural Classification Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Source classification Plants Naphthalene Quinones Disease Research Fields Cancer	STAT Autophagy
Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC₅₀ of 4.6 μM.

Salvianolic acid F	Structural Classification Stilbenes Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Others
Salvianolic acid F is a kind of Salvianolic Acids. Salvianolic Acids is the most effective and abundant compounds extracted from Salvia miltiorrhiza, with good anti-oxidative activity .

Trijuganone C	Quinones Structural Classification Labiatae Source classification Samanea saman (Jacq.) Merr. Benzene Quinones Plants Naphthalene Quinones	Caspase
Trijuganone C, a natural product extracted from Salvia miltiorrhiza, inhibits the proliferation of cancer cells through induction of apoptosis mediated by mitochondrial dysfunction and caspase activation .

Methyl tanshinonate	Structural Classification Natural Products Labiatae Source classification Samanea saman (Jacq.) Merr. Plants	SARS-CoV
Methyl tanshinonate is a tanshinone, that can be isolated from Salvia miltiorrhiza (S. miltiorrhiza) Bunge (Lamiaceae). Methyl tanshinonate is a potent inhibitor of M ^pro enzyme in SARS-CoV (IC₅₀ = 21.1 µM). Methyl tanshinonate can be used for diabetes and SARS-CoV research .

Salvianolic acid B 5+ Cited Publications Lithospermic acid B	Cardiovascular Disease Structural Classification Classification of Application Fields Labiatae Samanea saman (Jacq.) Merr. Source classification Phenols Polyphenols Plants Disease Research Fields	Autophagy
Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication.

Tanshinone IIA 10+ Cited Publications Dan Shen ketone	Quinones Structural Classification Classification of Application Fields Terpenoids Labiatae Samanea saman (Jacq.) Merr. Source classification Diterpenoids Plants Naphthalene Quinones Disease Research Fields Cancer	VEGFR
Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF/VEGFR2.

Salvianolic acid D (Standard)	Structural Classification Labiatae Samanea saman (Jacq.) Merr. Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants	Others
Salvianolic acid D (Standard) is the analytical standard of Salvianolic acid D. This product is intended for research and analytical applications. Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .

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Salvia miltiorrhiza

Inhibitors & Agonists

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Natural
Products