2. Natural Products
  3. Plants
  4. Celastraceae

Celastraceae

 

Celastraceae (120):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-13067
    Celastrol 34157-83-0 99.90%
    Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH.
    Celastrol
  • HY-32735
    Triptolide 38748-32-2 99.86%
    Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.
    Triptolide
  • HY-N0587
    Demethylzeylasteral 107316-88-1 99.92%
    Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation [1][2].
    Demethylzeylasteral
  • HY-32736
    Triptonide 38647-11-9 99.89%
    Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3?nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects.
    Triptonide
  • HY-13674
    Maytansine 35846-53-8 99.81%
    Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations.
    Maytansine
  • HY-124915
    Netzahualcoyondiol 113579-08-1
    Netzahualcoyondiol is a triterpene that can be isolated from m root bark of Cheiloclinium cognatum.
    Netzahualcoyondiol
  • HY-N6635R
    trans-Nerolidol (Standard) 40716-66-3
    trans-Nerolidol (Standard) is the analytical standard of trans-Nerolidol. This product is intended for research and analytical applications. trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity.
    trans-Nerolidol (Standard)
  • HY-N0475R
    Triptophenolide (Standard) 74285-86-2
    Triptophenolide (Standard) is the analytical standard of Triptophenolide. This product is intended for research and analytical applications.
    Triptophenolide (Standard)
  • HY-N1937
    Pristimerin 1258-84-0 99.22%
    Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM.
    Pristimerin
  • HY-N2922
    β-Amyrin 559-70-6 99.58%
    β-Amyrin, an ingredient of Celastrus hindsii, blocks amyloid β (Aβ)-induced long-term potentiation (LTP) impairment. β-amyrin is a promising candidate of treatment for AD.
    β-Amyrin
  • HY-117469
    Triptohypol C 193957-88-9
    Triptohypol C, a Tripterin (HY-13067) derivative, is a potent Nur77-targeting anti-inflammatory agent with an Kd value of 0.87 μM. Triptohypol C inhibits inflammatory response by promoting the interactions of Nur77 with TRAF2 and p62/SQSTM1.
    Triptohypol C
  • HY-N6635
    trans-Nerolidol 40716-66-3
    trans-Nerolidol is a sesquiterpene alcohol. It can be isolated from f aerial parts of Warionia saharae ex Benth. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (HY-15142A) against intestinal cancer cells in vitro. trans-Nerolidol also has anti-fungal activity.
    trans-Nerolidol
  • HY-N4110
    Friedelin 559-74-0 ≥99.0%
    Friedelin is derived from the leaves of Maytenus ilicifolia (Mart). Friedelin is an orally active non-competitive inhibitor of CYP3A4, with IC50 and Ki values of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1, with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively. Friedelin can be used in research related to inflammation, neurological diseases, and metabolic disorders.
    Friedelin
  • HY-N0476
    Wilforlide A 84104-71-2 ≥98.0%
    Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects.
    Wilforlide A
  • HY-N0475
    Triptophenolide 74285-86-2 99.93%
    Triptophenolide is a colorless crystalline plate isolated from ethyl acetate extracts of Tripterygium wilfordii.
    Triptophenolide
  • HY-N0899
    Wilforine 11088-09-8 99.47%
    Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T.
    Wilforine
  • HY-N10851
    23-Nor-6-oxopristimerol 118172-79-5
    23-Nor-6-oxopristimerol is a phenolic dinor-triterpene.
    23-Nor-6-oxopristimerol
  • HY-N3506
    Wilfortrine 37239-48-8 98.83%
    Wilfortrine is a bioactive sesquiterpene alkaloid. Wilfortrine exhibits immunosuppresive effects. Wilfortrine also can inhibit leukaemia cell growth in mice and shows anti-HIV activity.
    Wilfortrine
  • HY-N8879
    Wilforol A 167882-66-8 98.64%
    Wilforol A ((-)-Wilforol A), plant metabolite, is a pentacyclic triterpenoid. Wilforol A can be used for the research of various biochemical studies.
    Wilforol A
  • HY-N1072
    Wilforgine 37239-47-7 99.67%
    Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
    Wilforgine