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Taxol

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (2) Apoptosis (3) Cytochrome P450 (2) Fluorescent Dye (1) HIV (1) Isotope-Labeled Compounds (1) Microtubule/Tubulin (6) P-glycoprotein (1) PROTACs (1)
By Research Areas:	Cancer (17) Infection (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0227

7-epi-Taxol 2 Publications Verification 7-epi-Paclitaxel	Microtubule/Tubulin	Cancer
7-epi-Taxol is an active metabolite of taxol, with activity comparable to that of taxol against cell replication, promoting microtubule bundle formation and against microtubule depolymerization.

HY-N2380

N-Benzoyl-(2R,3S)-3-phenylisoserine	Others	Cancer
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol .

HY-16565

10-Deacetylbaccatin III	Others	Cancer
10-Deacetylbaccatin-III is an intermediate for taxol analog preparations.

HY-77434

9-Dihydro-13-acetylbaccatin III 9-DHAB III; 13-Acetyl-9-dihydrobaccatin III	Others	Cancer
9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.

HY-77572

7-Epi 10-desacetyl paclitaxel 7-epi-10-deacetylTaxol; 10-Deacetyl-7-epipaclitaxel	ADC Cytotoxin	Cancer
7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC₅₀ of 85 μM .

HY-77574

7-xylosyltaxol 7-Xylosylpaclitaxel; Taxol-7-xyloside	Microtubule/Tubulin	Cancer
7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules.

HY-D1386

*JF526-Taxol* TFA**	Fluorescent Dye	Others
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .

HY-158429

PROTAC CYP1B1 degrader-2	PROTACs Cytochrome P450	Cancer
PROTAC CYP1B1 degrader-2 (compound PV2) is a von Hippel-Landau (VHL) E3 ligase-based CYP1B1 degrader with the DC₅₀ of 1.0 nM at 24 h in A549/Taxol cells. PROTAC CYP1B1 degrader-2 inhibits growth, migration, and invasion of A549/Taxol cell(Sturcture Note:(Blue: VHL ligand (HY-112078), Black: linker (HY-W007700), Pink: CYP1B1 ligand (HY-159006) .

HY-N7289

Taxuspine B	Others	Cancer
Taxuspine B is a natural product, that can be isolated from Japanese yew Taxus. Taxuspine B exhibits appreciable taxol-like activity to reduce CaCl₂-induced depolymerixation of microtubules among the taxoids .

HY-162098

PROTAC tubulin-Degrader-1	Microtubule/Tubulin	Cancer
PROTAC tubulin-IN-1 (compound W13) is an inhibitor of PROTAC tubulin. PROTAC tubulin-IN-1 exhibits antitumor activity against human lung cancer .

HY-168008

P-gp inhibitor 25	P-glycoprotein	Cancer
P-gp inhibitor 25 (compound 16c) is a P-gp inhibitor. P-gp inhibitor 25 can enhance the oral absorption of paclitaxel (HY-B0015). P-gp inhibitor 25 can be used in anti-cancer research .

HY-W009245

Bz-RS-iSer(3-Ph)-OMe	HIV	Infection
Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation .

HY-159006

CYP1B1 ligand 3	Cytochrome P450	Cancer
CYP1B1 ligand 3 (Compound A1) is a selective inhibitor for cytochrome P450 enzyme CYP1B1 with an IC₅₀ of 11.9 nM. CYP1B1 ligand 3 can be utilized for the synthesis of PROTAC CYP1B1 degrader-2 (HY-158429) .

HY-B0011A

Docetaxel Trihydrate 95+ Cited Publications RP-56976 Trihydrate	Microtubule/Tubulin Apoptosis	Cancer
Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC₅₀ value of 0.2 μM . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis .

HY-77572R

7-Epi 10-desacetyl paclitaxel (Standard)	ADC Cytotoxin	Cancer
7-Epi 10-desacetyl paclitaxel (Standard) is the analytical standard of 7-Epi 10-desacetyl paclitaxel. This product is intended for research and analytical applications. 7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM .

HY-B0011AS

Docetaxel-d5 trihydrate RP-56976-d₅ trihydrate	Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis	Cancer
Docetaxel-d₅ (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].

HY-B0011AR

Docetaxel Trihydrate (Standard)	Microtubule/Tubulin Apoptosis	Cancer
Docetaxel (Trihydrate) (Standard) is the analytical standard of Docetaxel (Trihydrate). This product is intended for research and analytical applications. Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule?depolymerization with an IC₅₀ value of 0.2 μM . Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of?bcl-2?and?bcl-xL?gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis .

HY-118487A

OB-24 free base	Others	Cancer
OB-24 free base is a compound that potently and selectively inhibits heme oxygenase 1 (HO-1) and has the potential to inhibit advanced prostate cancer. OB-24 significantly reduces protein carbonylation and the formation of reactive oxygen species by selectively inhibiting HO-1 activity in prostate cancer cells. OB-24 significantly inhibited cell proliferation in vitro and inhibited tumor growth and lymph node and lung metastasis in vivo. OB-24 exhibits powerful synergy when used in combination with Taxol .

Cat. No.	Product Name	Type

HY-D2341

6FC-GABA-Taxol	Fluorescent Dyes/Probes
6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .

6FC-GABA-Taxol

Fluorescent Dyes/Probes

6FC-GABA-Taxol is a fluorescent probe with cell permeability, which is formed by connecting 6FC to the anticancer drug Taxol (HY-B0015) via γ-aminobutyric acid (GABA). 6FC-GABA-Taxol can bind to microtubules in living cells and image them through confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without the addition of efflux inhibitors .

HY-D1386

*JF526-Taxol* TFA**	Fluorescent Dyes/Probes
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0227

7-epi-Taxol 2 Publications Verification 7-epi-Paclitaxel	Structural Classification Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Microtubule/Tubulin
7-epi-Taxol is an active metabolite of taxol, with activity comparable to that of taxol against cell replication, promoting microtubule bundle formation and against microtubule depolymerization.

HY-N2380

N-Benzoyl-(2R,3S)-3-phenylisoserine	Alkaloids Structural Classification Classification of Application Fields Other Alkaloids Taxaceae Source classification Plants Disease Research Fields Taxus wallichiana Zucc. Cancer	Others
N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol .

HY-16565

10-Deacetylbaccatin III	Structural Classification Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	Others
10-Deacetylbaccatin-III is an intermediate for taxol analog preparations.

HY-77434

9-Dihydro-13-acetylbaccatin III 9-DHAB III; 13-Acetyl-9-dihydrobaccatin III	Classification of Application Fields Terpenoids Source classification Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.	Others
9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.

HY-77572

7-Epi 10-desacetyl paclitaxel 7-epi-10-deacetylTaxol; 10-Deacetyl-7-epipaclitaxel	Structural Classification Microorganisms Classification of Application Fields Terpenoids Taxaceae Source classification Diterpenoids Plants Disease Research Fields Taxus chinensis (Pilger) Rehd. Cancer	ADC Cytotoxin
7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC₅₀ of 85 μM .

HY-77574

7-xylosyltaxol 7-Xylosylpaclitaxel; Taxol-7-xyloside	Classification of Application Fields Terpenoids Source classification Taxaceae Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.	Microtubule/Tubulin
7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules.

HY-N7289

Taxuspine B	Structural Classification Taxus cuspidata Siebold & Zucc. Ketones, Aldehydes, Acids Source classification Taxaceae Plants	Others
Taxuspine B is a natural product, that can be isolated from Japanese yew Taxus. Taxuspine B exhibits appreciable taxol-like activity to reduce CaCl₂-induced depolymerixation of microtubules among the taxoids .

HY-77572R

7-Epi 10-desacetyl paclitaxel (Standard)	Structural Classification Microorganisms Terpenoids Taxaceae Source classification Diterpenoids Plants Taxus chinensis (Pilger) Rehd.	ADC Cytotoxin
7-Epi 10-desacetyl paclitaxel (Standard) is the analytical standard of 7-Epi 10-desacetyl paclitaxel. This product is intended for research and analytical applications. 7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM .

Cat. No.	Product Name	Chemical Structure

HY-B0011AS

Docetaxel-d5 trihydrate
Docetaxel-d₅ (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].

Docetaxel-d5 trihydrate

Docetaxel-d₅ (trihydrate) is the deuterium labeled Docetaxel (Trihydrate). Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC50 value of 0.2 μM[1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis[1][3].

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Taxol

Inhibitors & Agonists

Fluorescent Dye

NaturalProducts

Isotope-Labeled Compounds

Natural
Products