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Results for "

leucine metabolism

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W012708
    3-Amino-4-methylpentanoic acid

    		Endogenous Metabolite Others
    3-Amino-4-methylpentanoic acid is a beta amino acid and positional isomer of L-leucine which is naturally produced in humans via the metabolism of L-leucine by the enzyme leucine 2,3-aminomutase.
    3-Amino-4-methylpentanoic acid
  • HY-153040
    HPPE

    Bach1-IN-1

    		 Mitochondrial Metabolism Metabolic Disease
    HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD .
    HPPE
  • HY-W012722
    4-Methyl-2-oxopentanoic acid
    1 Publications Verification

    α-Ketoisocaproic acid

    		 Endogenous Metabolite Autophagy mTOR SOD Neurological Disease Metabolic Disease
    4-Methyl-2-oxopentanoic acid (α-Ketoisocaproic acid) is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways. 4-Methyl-2-oxopentanoic acid also causes oxidative damage, leading to cognitive deficits, inhibits α-ketoglutarate dehydrogenase activity, acts as an oxidative phosphorylation uncoupler and metabolic inhibitor. 4-Methyl-2-oxopentanoic acid acts as a nutrient signal and stimulates skeletal muscle protein synthesis. 4-Methyl-2-oxopentanoic acid can be used in the study of maple syrup urine disease .
    4-Methyl-2-oxopentanoic acid
  • HY-134425
    β-Methylcrotonyl coenzyme A lithium

    		Endogenous Metabolite Metabolic Disease
    β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .
    β-Methylcrotonyl coenzyme A lithium

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