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Results for "

lysoPAF

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

3

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-141570
    Lyso-PAF C-16

    		Others Others
    Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid .
    Lyso-PAF C-16
  • HY-141581
    Lyso-PAF C-18

    		Platelet-activating Factor Receptor (PAFR) Endogenous Metabolite Cardiovascular Disease
    Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345). It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties .
    Lyso-PAF C-18
  • HY-141570S
    Lyso-PAF C-16-d4

    Lyso-platelet-activating factor C-16-d4

    		 Isotope-Labeled Compounds Others
    Lyso-PAF C-16-d4 is the deuterium labeled Lyso-PAF C-16[1].
    Lyso-PAF C-16-d4
  • HY-N8489
    1-Methoxyphaseollidin

    		Endogenous Metabolite Bacterial Infection
    1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains .
    1-Methoxyphaseollidin
  • HY-112825
    TSI-01

    		Others Inflammation/Immunology
    Platelet-activating factor (PAF) is a pro-inflammatory phospholipid mediator that is rapidly synthesized by lyso-PAF acetyltransferase (lyso-PAFAT) in response to extracellular stimuli. Two types of lyso-PAFAT have been identified: lysophosphatidylcholine acyltransferase (LPCAT)1, which is mostly expressed in the lungs, and LPCAT2, which is expressed in inflammatory cells. TSI-01 is a selective inhibitor of LPCAT2 (IC50s=0.47 versus 3.02 μM for human LPCAT2 and LPCAT1, respectively). 60 μM it is shown to suppress PAF biosynthesis in mouse peritoneal macrophages stimulated with a calcium ionophore.
    TSI-01
  • HY-141581S
    Lyso-PAF C-18-d4

    		Isotope-Labeled Compounds Others
    Lyso-PAF C-18-d4 is the deuterium labeled Lyso-PAF C-18[1].
    Lyso-PAF C-18-d4

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