2. Metabolic Enzyme/Protease Anti-infection
  3. Endogenous Metabolite Bacterial
  4. 1-Methoxyphaseollidin

1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.

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1-Methoxyphaseollidin Chemical Structure

1-Methoxyphaseollidin Chemical Structure

CAS No. : 65428-13-9

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1-Methoxyphaseollidin Related Antibodies

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Description

1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

354.40

Formula

C21H22O5
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC(OC)=C2[C@@](OC3=C(C/C=C(C)\C)C(O)=CC=C34)([H])[C@@]4([H])COC2=C1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 18 mg/mL (50.79 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8217 mL 14.1084 mL 28.2167 mL
5 mM 0.5643 mL 2.8217 mL 5.6433 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8217 mL 14.1084 mL 28.2167 mL 70.5418 mL
5 mM 0.5643 mL 2.8217 mL 5.6433 mL 14.1084 mL
10 mM 0.2822 mL 1.4108 mL 2.8217 mL 7.0542 mL
15 mM 0.1881 mL 0.9406 mL 1.8811 mL 4.7028 mL
20 mM 0.1411 mL 0.7054 mL 1.4108 mL 3.5271 mL
25 mM 0.1129 mL 0.5643 mL 1.1287 mL 2.8217 mL
30 mM 0.0941 mL 0.4703 mL 0.9406 mL 2.3514 mL
40 mM 0.0705 mL 0.3527 mL 0.7054 mL 1.7635 mL
50 mM 0.0564 mL 0.2822 mL 0.5643 mL 1.4108 mL
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1-Methoxyphaseollidin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Methoxyphaseollidin65428-13-9Endogenous MetaboliteBacteriallysoPAFacetyltransferaseH.pyloriInhibitorinhibitorinhibit

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