microbial metabolism

By Targets:	Bacterial (1) Endogenous Metabolite (9) Ferroptosis (2)
By Research Areas:	Cancer (1) Endocrinology (1) Infection (1) Inflammation/Immunology (2) Metabolic Disease (2)
Oligonucleotides:	Cholesterol (1)

Targets Recommended: Mitochondrial Metabolism

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0172B

Isolithocholic acid	Endogenous Metabolite	Endocrinology
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .

HY-W015969

1-Aminopropan-2-ol Monoisopropanolamine	Endogenous Metabolite	Metabolic Disease
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-Y0520

Itaconic acid 1 Publications Verification Methylenesuccinic acid	Endogenous Metabolite Ferroptosis	Inflammation/Immunology Cancer
Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .

HY-126574

Pantothenoylcysteine	Endogenous Metabolite	Others
Pantothenoylcysteine is the biosynthetic precursor of CoA. Pantothenoylcysteine can be used to study microbial metabolism .

HY-W403633

Hexahydrohippuric acid	Bacterial	Infection
Hexahydrohippuric acid is a metabolite of Shikimate acid in both liver and kidney, under microbial metabolism effect. Hexahydrohippuric acid is made of cyclohexane carboxylic acid and glycinamide, and shows antibacterial activity .

HY-N10475

4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone	Endogenous Metabolite	Others
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone (compound 3) is a hydroxylated microbial metabolite of Yangonin .

HY-41325

7,12-Diketolithocholic acid 7,12-Dioxolithocholic acid; 3-Hydroxy-7,12-diketocholanoic acid; 7,12-Diketo-LCA	Endogenous Metabolite	Others
7,12-Diketolithocholic acid (7,12-Diketo-LCA) is a bile acid, which can be produced in the host-gut microbial co-metabolism of the bile acid pool .

HY-W015969R

1-Aminopropan-2-ol (Standard)	Endogenous Metabolite	Metabolic Disease
1-Aminopropan-2-ol (Standard) is the analytical standard of 1-Aminopropan-2-ol. This product is intended for research and analytical applications. 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-138933

(±)-Geosmin	Endogenous Metabolite
(±)-Geosmin is a natural organic compound with biological activity that causes earthy aroma. (±)-Geosmin plays an important role in microbial metabolism and is commonly used as a fragrance in food and air. (±)-Geosmin has also been studied for detecting soil and water pollution.

HY-Y0520R

Itaconic acid (Standard) Methylenesuccinic acid (Standard)	Endogenous Metabolite Ferroptosis	Inflammation/Immunology
Itaconic acid (Standard) is the analytical standard of Itaconic acid. This product is intended for research and analytical applications. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .

HY-N7921

Urolithin M6	Others	Others
Urolithin M6 is a polyhydroxy-rich metabolite with potential antioxidant activity. Urolithin M6 is produced by intestinal microbial metabolism and may act as an analog of tannic acid compounds. The production of Urolithin M6 in humans requires specific bacterial 3-dehydroxylase activity, which provides a new mechanism for its biotransformation. The metabolic profile of Urolithin M6 helps to stratify volunteers and further explore its potential role in health and disease .

Cat. No.	Product Name

HY-L078

Gut Microbial Metabolite Library	510 compounds
Accumulating evidence has revealed that intestinal microbiota play an important role in human health and disease, including cardiovascular diseases, inflammatory bowel disease, diabetes, obesity, cancer, and depression, etc. Changes in the composition of gut microbiota associated with disease, referred to as dysbiosis, have been linked to pathologies. Indeed, the gut microbiome functions like an endocrine organ, generating bioactive metabolites which play important roles in human metabolism, health, and disease. Gut microbiome has become a novel therapeutic target for many diseases. Analysis and identification of gut microbial metabolite will contribute to the development of therapeutic methods. In order to meet the need of gut microbiome research, MCE carefully selected a unique collection of 510 gut microbial metabolites. MCE gut microbial metabolite library is a powerful tool for gut microbiome research and gut microbiome -related drug discovery.

Gut Microbial Metabolite Library

510 compounds

Accumulating evidence has revealed that intestinal microbiota play an important role in human health and disease, including cardiovascular diseases, inflammatory bowel disease, diabetes, obesity, cancer, and depression, etc. Changes in the composition of gut microbiota associated with disease, referred to as dysbiosis, have been linked to pathologies. Indeed, the gut microbiome functions like an endocrine organ, generating bioactive metabolites which play important roles in human metabolism, health, and disease. Gut microbiome has become a novel therapeutic target for many diseases. Analysis and identification of gut microbial metabolite will contribute to the development of therapeutic methods.

In order to meet the need of gut microbiome research, MCE carefully selected a unique collection of 510 gut microbial metabolites. MCE gut microbial metabolite library is a powerful tool for gut microbiome research and gut microbiome -related drug discovery.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0172B

Isolithocholic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .

HY-W015969

1-Aminopropan-2-ol Monoisopropanolamine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-Y0520

Itaconic acid 1 Publications Verification Methylenesuccinic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Ferroptosis
Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .

HY-N10475

4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone	Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Piperaceae Piper methysticum G.Forst. Plants Disease Research Fields	Endogenous Metabolite
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone (compound 3) is a hydroxylated microbial metabolite of Yangonin .

HY-W015969R

1-Aminopropan-2-ol (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
1-Aminopropan-2-ol (Standard) is the analytical standard of 1-Aminopropan-2-ol. This product is intended for research and analytical applications. 1-Aminopropan-2-ol is a microbial metabolism of amino alcohol metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas .

HY-Y0520R

Itaconic acid (Standard) Methylenesuccinic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite	Endogenous Metabolite Ferroptosis
Itaconic acid (Standard) is the analytical standard of Itaconic acid. This product is intended for research and analytical applications. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .

HY-N7921

Urolithin M6	Structural Classification Monophenols Source classification Phenols Endogenous metabolite	Others
Urolithin M6 is a polyhydroxy-rich metabolite with potential antioxidant activity. Urolithin M6 is produced by intestinal microbial metabolism and may act as an analog of tannic acid compounds. The production of Urolithin M6 in humans requires specific bacterial 3-dehydroxylase activity, which provides a new mechanism for its biotransformation. The metabolic profile of Urolithin M6 helps to stratify volunteers and further explore its potential role in health and disease .

Cat. No.	Product Name		Classification

HY-B0172B

Isolithocholic acid		Cholesterol
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .

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microbial metabolism

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