2. Oligonucleotides
  3. Cholesterol

Cholesterol

Cholesterol is a sterol, a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell membranes. Cholesterol is a membrane constituent widely found in biological systems and serves the unique purpose of modulating membrane fluidity, elasticity, as well as permeability. The addition of cholesterol to liposome bilayers prevents a lipid exchange and has an additional stabilizing effect.

Cholesterol (33):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0322A
    Cholesterol (Water Soluble) ≥98.0%
    Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells.
    Cholesterol (Water Soluble)
  • HY-N0131
    Stigmasterol 83-48-7 ≥98.0%
    Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.
    Stigmasterol
  • HY-N1459
    Campesterol 474-62-4 99.42%
    Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects.
    Campesterol
  • HY-N4103
    Fucosterol 17605-67-3 98.27%
    Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research.
    Fucosterol
  • HY-N0181
    Ergosterol 57-87-4 99.17%
    Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
    Ergosterol
  • HY-121799A
    Taurohyocholic acid sodium salt 117997-17-8
    Taurohyocholic acid (THCA) sodium salt is a taurine-conjugated hyocholic acid. Taurohyocholic acid sodium salt is predictor of the efficacy of tyrosine kinase inhibitors combined withPD-1 inhibitors in hepatocellular carcinoma (HCC).
    Taurohyocholic acid sodium salt
  • HY-138912
    Cho-Arg TFA 1609010-56-1
    Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy.
    Cho-Arg TFA
  • HY-N0171
    Beta-Sitosterol (purity>80%) 83-46-5 ≥98.0%
    Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>80%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation.
    Beta-Sitosterol (purity>80%)
  • HY-W010800
    Cholesteryl hemisuccinate 1510-21-0 99.70%
    Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth.
    Cholesteryl hemisuccinate
  • HY-B0172B
    Isolithocholic acid 1534-35-6 98.70%
    Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate.
    Isolithocholic acid
  • HY-137131
    DC-Chol hydrochloride 166023-21-8 99.91%
    DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner.
    DC-Chol hydrochloride
  • HY-113217
    Cholesteryl oleate 303-43-5 ≥99.0%
    Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy).
    Cholesteryl oleate
  • HY-113289
    Brassicasterol 474-67-9 98.71%
    Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease.
    Brassicasterol
  • HY-133971
    Cholesterol 5α,6α-epoxide 1250-95-9 98.40%
    Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.
    Cholesterol 5α,6α-epoxide
  • HY-W127351
    Cholesterol decanoate 1183-04-6 ≥98.0%
    Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.
    Cholesterol decanoate
  • HY-151705
    Alkyne Cholesterol 1631985-09-5
    Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization.
    Alkyne Cholesterol
  • HY-144768
    (R)-Chol-TPP
    (R)-Chol-TPP a mitochondria targeting liposome ligand could be used in pH-redox responsive.
    (R)-Chol-TPP
  • HY-N2338
    Cholesterol myristate 1989-52-2 ≥98.0%
    Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.
    Cholesterol myristate
  • HY-W127558
    Cholesterol-PEG 600 69068-97-9
    Cholesterol-PEG 600 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cholesterol-PEG 600
  • HY-156197
    Biotin-cholesterol 2454045-15-7
    Biotin-cholesterol is a biotinylated form of Cholesterol (HY-N0322). Biotin-cholesterol can be used in the synthesis of biotin-conjugated liposomes and micelles for drug delivery.
    Biotin-cholesterol