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Results for "

mitochondrial transmembrane potential

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

3

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1925A
    GO-203 TFA
    2 Publications Verification

    		 PI3K Reactive Oxygen Species Apoptosis Cancer
    GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
    GO-203 TFA
  • HY-N4104
    Agaric acid

    Agaricinic Acid

    		 Mitochondrial Metabolism Metabolic Disease
    Agaric acid (Agaricinic Acid) is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Agaric acid promotes efflux of accumulated Ca 2+, collapse of transmembrane potential, and mitochondrial swelling. Agaric acid is used to regulate lipid metabolism .
    Agaric acid
  • HY-W002620A
    Emoxypine succinate

    2-Ethyl-3-hydroxy-6-methylpyridine succinate

    		 Reactive Oxygen Species Infection Inflammation/Immunology
    Emoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic .
    Emoxypine succinate
  • HY-N8551
    (5E)-7-Oxozeaenol

    		Others Infection Cancer
    (5E)-7-Oxozeaenol is an active fungal extract that is cytotoxic. (5E)-7-Oxozeaenol exhibits antibacterial, mitochondrial transmembrane potential, and NF-κB effects .
    (5E)-7-Oxozeaenol
  • HY-N12985
    Procyanidin B7

    		Others Metabolic Disease
    Procyanidin B7 can be isolated from Solix sieboldiana. Procyanidin B7 ameliorates Dexamethasone (HY-14648)-induced mitochondrial deficits in 3T3-L1 adipocytes, via improving mitochondrial biogenesis, dynamics, transmembrane potential, and antioxidant defenses .
    Procyanidin B7
  • HY-137038
    N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride

    TLCK hydrochloride

    		 Caspase Ser/Thr Protease Cancer
    N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride (TLCK hydrochloride) is an irreversible inhibitor for serine protease, which inhibits trypsin and trypsin-like protease by alkylating histidine residues in their active site. N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride inhibits caspase-3, caspase-6 and caspase-7, with IC50s of 12.0, 54.5 and 19.3 μM, respectively. N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride induces apoptosis in cell HL-60, and inhibits the decrease in mitochondrial transmembrane potential during apoptosis .
    N-a-Tosyl-L-lysinyl-chloromethylketone hydrochloride

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