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  3. Mal-β-CD

Mal-β-CD  (Synonyms: 6-O-alpha-D-Maltosyl-beta-cyclodextrin)

Cat. No.: HY-18593 Purity: ≥98.0%
COA Handling Instructions

Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.

For research use only. We do not sell to patients.

Mal-β-CD Chemical Structure

Mal-β-CD Chemical Structure

CAS No. : 104723-60-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
500 mg USD 30 In-stock
1 g USD 40 In-stock
5 g USD 80 In-stock
10 g   Get quote  
50 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

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Description

Mal-β-CD is a cellular cholesterol modifier which can form soluble inclusion complex with cholesterol.

In Vitro

Mal-β-CD removes cellular cholesterol forming inclusion complexes, while Mal-β-CD-induced lack of cellular cholesterol is replenished by the addition of cholesterol/Mal-β-CD inclusion complex (CLM) without cytotoxicity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1459.27

Formula

C54H90O45

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@@H](CO)O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](OC[C@H]3O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O6)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@@H](O)[C@@H]3O[C@H]7O[C@H](CO)[C@@H](O[C@@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]9[C@H](O)[C@@H](O)[C@H](OC%10[C@H](O)[C@@H](O)[C@H]6[C@@H](CO)O%10)[C@@H](CO)O9)[C@@H](CO)O8)[C@H](O)[C@H]7O)O[C@@H]2CO)[C@H](O)[C@H]1O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (68.53 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 60.5 mg/mL (41.46 mM)

*"≥" means soluble, but saturation unknown.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C1

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Volume (start)

V1

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 0.6853 mL 3.4264 mL 6.8527 mL 17.1319 mL
5 mM 0.1371 mL 0.6853 mL 1.3705 mL 3.4264 mL
10 mM 0.0685 mL 0.3426 mL 0.6853 mL 1.7132 mL
15 mM 0.0457 mL 0.2284 mL 0.4568 mL 1.1421 mL
20 mM 0.0343 mL 0.1713 mL 0.3426 mL 0.8566 mL
25 mM 0.0274 mL 0.1371 mL 0.2741 mL 0.6853 mL
30 mM 0.0228 mL 0.1142 mL 0.2284 mL 0.5711 mL
40 mM 0.0171 mL 0.0857 mL 0.1713 mL 0.4283 mL
DMSO 50 mM 0.0137 mL 0.0685 mL 0.1371 mL 0.3426 mL
60 mM 0.0114 mL 0.0571 mL 0.1142 mL 0.2855 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mal-β-CD
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HY-18593
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