2. Anti-infection Neuronal Signaling
  3. Bacterial Cholinesterase (ChE)
  4. Dimethyl sulfoxide, meets analytical specification of Ch.P.

Dimethyl sulfoxide, meets analytical specification of Ch.P.  (Synonyms: DMSO, meets analytical specification of Ch.P.)

Cat. No.: HY-Y0320 Purity: 99.89%
SDS COA Handling Instructions

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Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties.
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

For research use only. We do not sell to patients.

Dimethyl sulfoxide, meets analytical specification of Ch.P. Chemical Structure

Dimethyl sulfoxide, meets analytical specification of Ch.P. Chemical Structure

CAS No. : 67-68-5

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Based on 150 publication(s) in Google Scholar

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Dimethyl sulfoxide, meets analytical specification of Ch.P. Related Antibodies

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150 Publications Citing Use of MCE Dimethyl sulfoxide, meets analytical specification of Ch.P.

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Description

Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties[1][2][3].
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

Cellular Effect
Cell Line Type Value Description References
HEK293 IC50
232 μM
Compound: DMSO
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
[PMID: 27108400]
HL-60 IC50
108 μM
Compound: DMSO
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
[PMID: 27108400]
LN-18 IC50
223 μM
Compound: DMSO
Antiproliferative activity against human LN18 cells after 48 hrs by MTT assay
Antiproliferative activity against human LN18 cells after 48 hrs by MTT assay
[PMID: 27108400]
MDCK-II GI50
123 μM
Compound: DMSO
Growth inhibition of MDCK2 cells after 72 hrs by MTT assay
Growth inhibition of MDCK2 cells after 72 hrs by MTT assay
[PMID: 32787102]
MDCK-II GI50
137 μM
Compound: DMSO
Growth inhibition of MDCK2 cells over expressing human ABCG2 after 72 hrs by MTT assay
Growth inhibition of MDCK2 cells over expressing human ABCG2 after 72 hrs by MTT assay
[PMID: 32787102]
THP-1 IC50
119 μM
Compound: DMSO
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay
[PMID: 27108400]
In Vitro

DMSO is an organic solvent that is freely miscible with water, lipids and organic agents. These properties allow for exceptional membrane penetration. The mechanism of action of DMSO is thought to be a combination of anti-inflammatory effects, nerve blockade, smooth muscle relaxation, and collagen inhibition[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dimethyl sulfoxide, meets analytical specification of Ch.P. Related Antibodies
Clinical Trial
Molecular Weight

78.13

Formula

C2H6OS
CAS No.
Appearance

<18.4°C Solid,>18.4°C Liquid

Color

Colorless to off-white

SMILES

O=S(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years
Purity & Documentation

Purity: 100.0%

SDS (393 KB)

COA (256 KB)

Handling Instructions (2659 KB)
References
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Dimethyl sulfoxide, meets analytical specification of Ch.P. Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dimethyl sulfoxide, meets analytical specification of Ch.P.67-68-5DMSO, meets analytical specification of Ch.P.BacterialCholinesterase (ChE)anti-freezingbacteriostaticanti-inflammatoryaproticsolventInhibitorinhibitorinhibit

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