2. Cell Cycle/DNA Damage
  3. Eukaryotic Initiation Factor (eIF)
  4. DMDA-PatA

DMDA-PatA is a small-molecule eIF4A inhibitor that represses translation in an mRNA-selective and ATP-independent manner by clamping eIF4A, a DEAD-box RNA binding protein, onto GNG motifs. DMDA-PatA is promising for research of cancers and viral infections.

For research use only. We do not sell to patients.

DMDA-PatA Chemical Structure

DMDA-PatA Chemical Structure

CAS No. : 1531593-48-2

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DMDA-PatA Related Antibodies

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Description

DMDA-PatA is a small-molecule eIF4A inhibitor that represses translation in an mRNA-selective and ATP-independent manner by clamping eIF4A, a DEAD-box RNA binding protein, onto GNG motifs. DMDA-PatA is promising for research of cancers and viral infections[1].

IC50 & Target

eIF4

 

Molecular Weight

526.73

Formula

C30H42N2O4S
CAS No.
SMILES

CC(/C=C/C(C)=C/CN(C)C)=C\[C@@H](OC(/C=C/C=C(C1)\C)=O)CC2=NC(CCCCC(O[C@H]1C)=O)=CS2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DMDA-PatA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMDA-PatA1531593-48-2Eukaryotic Initiation Factor (eIF)eIF4AtranslationGNG motifscancersviral infectionsInhibitorinhibitorinhibit

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