MOGAT1 - monoacylglycerol O-acyltransferase 1 Gene

Homo sapiens

Also known as MGAT1; DGAT2L; DGAT2L1

Gene ID: 116255 | Gene type: protein coding

About MOGAT1

Cytogenetic location: 2q36.1 Genomic coordinates (GRCh38): 2:222,671,658-222,709,930 (from NCBI)

This gene has 1 transcript (splice variant), 219 orthologues and 6 paralogues. Biased expression in gall bladder (RPKM 7.8) and fat (RPKM 0.6).

Summary

Acyl-CoA:monoacylglycerol Acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and Phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]

MOGAT1 Products(1)

mRNA	Protein	Name
NM_058165.3	NP_477513.2	2-acylglycerol O-acyltransferase 1

MOGAT1 Protein Structure

DAGAT

0
100
200
300
335 a.a.

Protein Preferred Names

Protein Names

2-acylglycerol O-acyltransferase 1

acyl-CoA:monoacylglycerol acyltransferase 1

Related Diseases

Diseases

Alias

Lipodystrophy, Congenital Generalized, Type 1

Congenital Generalized Lipodystrophy Type 1	Bscl1
CGL1	Berardinelli-Seip Congenital Lipodystrophy, Type 1
Brunzell Syndrome Agpat2-Related	Berardinelli-Seip Congenital Lipodystrophy Type 1
Lipodystrophy, Berardinelli-Seip Congenital, Type 1	Brunzell Syndrome, Agpat2-Related
Agpat2-Related Brunzell Syndrome	Congenital Generalized Lipodystrophy 1
Berardinelli-Seip Syndrome	Lipoatrophic Diabetes
Lipodystrophy Berardinelli Type	Total Lipodystrophy And Acromegaloid Gigantism
Lipodystrophy, Generalized, Congenital, Type 1	Familial Generalized Lipodystrophy
Lipoatrophic Diabetes Mellitus	Familial Partial Lipodystrophy, Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08584	MOGAT1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MOGAT1	VGNC	VGNC:80283
Canis familiaris	MOGAT1	VGNC	VGNC:43308
Mus musculus	MOGAT1	MGD	MGI:1915643
Macaca mulatta	MOGAT1	VGNC	VGNC:74791
Bos taurus	MOGAT1	VGNC	VGNC:31550
Rattus norvegicus	MOGAT1	RGD	RGD:1311644

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