2. Gene
  3. ECI1 - enoyl-CoA delta isomerase 1 Gene

ECI1 - enoyl-CoA delta isomerase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as DCI

Gene ID: 1632 | Gene type: protein coding

About ECI1

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,239,402-2,251,587 (from NCBI)

This gene has 7 transcripts (splice variants), 213 orthologues and 13 paralogues. Ubiquitous expression in kidney (RPKM 39.8), colon (RPKM 22.9) and 25 other tissues.

Summary

This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial Enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]

ECI1 Products(2)

mRNA Protein Name
NM_001178029.2 NP_001171500.1 enoyl-CoA delta isomerase 1, mitochondrial isoform 2 precursor
NM_001919.4 NP_001910.2 enoyl-CoA delta isomerase 1, mitochondrial isoform 1 precursor

ECI1 Protein Structure

ECH_1

ECH_1: Enoyl-CoA hydratase/isomerase (53 - 295)

  • 0
  • 100
  • 200
  • 302 a.a.
Protein Preferred Names Protein Names

enoyl-CoA delta isomerase 1, mitochondrial

3,2 trans-enoyl-Coenzyme A isomerase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04141 ECI1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ECI1 VGNC VGNC:28309
Felis catus ECI1 VGNC VGNC:80567
Mus musculus ECI1 MGD MGI:94871
Macaca mulatta ECI1 VGNC VGNC:81391
Rattus norvegicus ECI1 RGD RGD:61892
Canis familiaris ECI1 VGNC VGNC:54017