2. Gene
  3. NKX1-2 - NK1 homeobox 2 Gene

NKX1-2 - NK1 homeobox 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NKX-1.1; C10orf121; bB238F13.2

Gene ID: 390010 | Gene type: protein coding

About NKX1-2

This gene has 1 transcript (splice variant), 168 orthologues and 13 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NKX1-2 Products(1)

mRNA Protein Name
NM_001146340.3 NP_001139812.1 NK1 transcription factor-related protein 2

NKX1-2 Protein Structure

Homeobox

Homeobox: Homeobox domain (164 - 220)

  • 0
  • 100
  • 200
  • 310 a.a.
Protein Preferred Names Protein Names

NK1 transcription factor-related protein 2

NK1 transcription factor related, locus 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09326 NKX1-2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NKX1-2 VGNC VGNC:32098
Canis familiaris NKX1-2 VGNC VGNC:43832
Mus musculus NKX1-2 MGD MGI:104806
Rattus norvegicus NKX1-2 RGD RGD:1306744
Macaca mulatta NKX1-2 VGNC VGNC:106080