1. Gene
  2. HS3ST2 - heparan sulfate-glucosamine 3-sulfotransferase 2 Gene

HS3ST2 - heparan sulfate-glucosamine 3-sulfotransferase 2 Gene

Homo sapiens

Also known as 30ST2; 3OST2

Gene ID: 9956 | Gene type: protein coding

About HS3ST2

Cytogenetic location: 16p12.2 Genomic coordinates (GRCh38): 16:22,814,162-22,916,338 (from NCBI)

This gene has 2 transcripts (splice variants), 217 orthologues and 10 paralogues. Biased expression in brain (RPKM 12.4) and lung (RPKM 0.7).

Summary

Heparan sulfate biosynthetic Enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The Enzyme encoded by this gene is a member of the heparan sulfate biosynthetic Enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system. [provided by RefSeq, Jul 2008]

HS3ST2 Products(1)

mRNA Protein Name
NM_006043.2 NP_006034.1 heparan sulfate glucosamine 3-O-sulfotransferase 2

HS3ST2 Protein Structure

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (115 - 350)

  • 0
  • 100
  • 200
  • 300
  • 367 a.a.
Protein Preferred Names Protein Names

heparan sulfate glucosamine 3-O-sulfotransferase 2

3-OST-2

Orthologs Information

Species Symbol Source ID
Bos taurus HS3ST2 VGNC VGNC:29959
Rattus norvegicus HS3ST2 RGD RGD:727787
Canis familiaris HS3ST2 VGNC VGNC:41792
Mus musculus HS3ST2 MGD MGI:1333802