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Hp

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Compare Product Name Species Source
  • HY-P78589

    FGL1; Hepassocin; Hp-041; HFREP-1; LFIRE-1; HFREP1

    Cynomolgus HEK293
    FGL1 Protein, a potent immune suppressive molecule, inhibits antigen-specific T-cell activation as a major ligand for LAG3. It crucially contributes to LAG3-mediated T-cell inhibitory functions, independently of MHC class II. Secreted by hepatocytes, FGL1 also promotes their growth. The homodimeric form of the protein interacts with LAG3, specifically engaging with its Ig-like domains 1 and 2 through the Fibrinogen C-terminal domain. FGL1 Protein, Cynomolgus (HEK293, mFc) is the recombinant cynomolgus-derived FGL1 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of FGL1 Protein, Cynomolgus (HEK293, mFc) is 290 a.a., with molecular weight of 60-66 kDa.
  • HY-P77366

    Fibrinogen-like protein 1; FGL1; Hp-041; Hepassocin; HFREP-1; LFIRE-1

    Cynomolgus HEK293
    FGL1 is a specific hepatocyte mitogen, regulates the expression of proliferative factors, promoting liver regeneration and repairing liver injury. FGL1 inhibits T-cell activation by binding to LAG3. FGL1 promotes cell proliferation by activating the ERK/p-ERK pathway. FGL1 inhibits apoptosis of non-small cell lung cancer (NSCLC) cells by inhibiting PARP1/caspase 3 pathway. FGL1 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived FGL1 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P77367

    Fibrinogen-like protein 1; FGL1; Hp-041; Hepassocin; HFREP-1; LFIRE-1

    Cynomolgus Sf9 insect cells
    FGL1 is a specific hepatocyte mitogen, regulates the expression of proliferative factors, promoting liver regeneration and repairing liver injury. FGL1 inhibits T-cell activation by binding to LAG3. FGL1 promotes cell proliferation by activating the ERK/p-ERK pathway. FGL1 inhibits apoptosis of non-small cell lung cancer (NSCLC) cells by inhibiting PARP1/caspase 3 pathway. FGL1 Protein, Cynomolgus (sf9, His) is the recombinant cynomolgus-derived FGL1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of FGL1 Protein, Cynomolgus (sf9, His) is 312 a.a., with molecular weight of ~35.40 KDa.
  • HY-P701014

    Interleukin-9; IL-9; Cytokine P40; T-cell growth factor P40; Hp40; P40

    Cynomolgus HEK293
    IL-9 is secreted by T helper 2 lymphocytes, mast cells, and NKT cells and plays an important role in antiparasitic immune responses, affecting intestinal permeability, adaptive immunity, and T cell subset differentiation. It promotes TH17 cell and mast cell proliferation through IL9R and IL2RG receptor activation, triggering JAK1 and JAK3 kinases and subsequent STAT-mediated transcription. IL-9 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-9 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-9 Protein, Cynomolgus (HEK293, His) is 126 a.a., with molecular weight of 25-30 kDa.

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