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  • HY-P72907
    CD40L/CD154/TRAP Protein, Human (His)
    1 Publications Verification

    CD40 ligand; CD40-L; TRAP; CD154; Scd40L; TNFSF5

    		 Human E. coli
    CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human (His) has a total length of 144 amino acids (E108-L261), is expressed in E. coli cells with C-terminal His-tag.
  • HY-P70537
    CD4 Protein, Human (365a.a, HEK293, His)

    T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; Scd4

    		 Human HEK293
    CD4 Protein is an integrated membrane glycoprotein that plays various roles in immune responses and defending against internal and external attacks. The alpha-helix structure of CD4 Protein and HIV-1 Vpu can be involved in the binding and degradation of CD4 molecules. CD4 Protein participates in the differentiation/activation, cytokine expression, and cell migration in macrophages or NK cells through a TCR/LCK-independent pathway. CD4 Protein can enhance the host's immune response to viral infections and boost anti-tumor immunity. CD4 Protein, Human (365 a.a, HEK293, His) is a recombinant CD4 protein with a His tag, expressed in HEK293. CD4 Protein, Human (365 a.a, HEK293, His) consists of 365 amino acids, with a molecular weight ranging from 49-58 kDa.
  • HY-P77884
    CD163 Protein, Human (HEK293, His-Avi)

    M130; CD163 molecule; CD163; GHI/61; HbSR; MM130; RM3/1; SCARI1; Scd163

    		 Human HEK293
    The CD163 protein is an acute-phase regulatory receptor that clears hemoglobin/haptoglobin complexes through endocytosis by macrophages, protecting tissues from potential oxidative damage. In addition to iron uptake, CD163 also exhibits calcium- and pH-dependent binding preferences, with higher affinity for the hemoglobin/haptoglobin complex of the HP*1F phenotype. CD163 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CD163 protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of CD163 Protein, Human (HEK293, His-Avi) is 1004 a.a., with molecular weight of 120-140 kDa.
  • HY-P78934
    CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, Fc-Avi)

    CD40 ligand; CD40-L; TRAP; CD154; Scd40L; TNFSF5

    		 Human HEK293
    CD40L/CD154/TRAP proteins stimulate T cell proliferation and cytokine production, acting as ligands for integrins and CD40 receptors to activate various cell-dependent effects such as B cell activation and NF-κ-B signaling. CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived CD40L/CD154/TRAP protein, expressed by HEK293 , with N-hFc, N-Avi labeled tag. The total length of CD40L/CD154/TRAP Protein, Human (Biotinylated, HEK293, Fc-Avi) is 149 a.a., with molecular weight of 50-55 kDa.
  • HY-P72907AF
    Animal-Free CD40L/CD154/TRAP Protein, Human (His)

    soluble CD40 Ligand; CD40 ligand; CD40-L; TRAP; CD154; Scd40L; TNFSF5

    		 Human E. coli
    CD40L/CD154/TRAP proteins stimulate T cell proliferation and cytokine production, acting as ligands for integrins and CD40 receptors to activate various cell-dependent effects such as B cell activation and NF-κ-B signaling. Animal-Free CD40L/CD154/TRAP Protein, Human (His) is the recombinant human-derived animal-FreeCD40L/CD154/TRAP protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free CD40L/CD154/TRAP Protein, Human (His) is 154 a.a., with molecular weight of ~16.99 kDa.
  • HY-P72028
    CD40L/CD154/TRAP Protein, Human (HEK293, hFc-Flag)

    CD40-L; T-cell antigen Gp39; NF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; Scd40L;

    		Human HEK293
    CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway. CD40L also involves in B cell differentiation, maturation, and apoptosis. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human (HEK293, hFc-Flag) has a total length of 248 amino acids (M13-L261), is expressed in HEK392 cells with N-terminal hFc- and Flag-tag.
  • HY-P72028A
    CD40L/CD154/TRAP Protein, Human (HEK293, N-hFc)

    CD40-L; T-cell antigen Gp39; NF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; Scd40L;

    		Human HEK293
    CD40L/CD154/TRAP proteins stimulate T cell proliferation and cytokine production, acting as ligands for integrins and CD40 receptors to activate various cell-dependent effects such as B cell activation and NF-κ-B signaling. CD40L/CD154/TRAP Protein, Human (HEK293, N-hFc) is the recombinant human-derived CD40L/CD154/TRAP protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD40L/CD154/TRAP Protein, Human (HEK293, N-hFc) is 149 a.a., with molecular weight of ~49 kDa.
  • HY-P700668
    CD163 Protein, Human (Biotinylated, HEK293, His-Avi)

    M130; CD163 molecule; CD163; GHI/61; HbSR; MM130; RM3/1; SCARI1; Scd163

    		 Human HEK293
    CD163 Protein, an acute phase-regulated receptor, crucially clears hemoglobin/haptoglobin complexes via endocytosis in macrophages, protecting tissues from potential oxidative damage. Beyond iron uptake, CD163 exhibits calcium- and pH-dependent binding preferences, with higher affinity for hemoglobin/haptoglobin complexes of HP*1F phenotype. It triggers intracellular signals, including tyrosine kinase-dependent calcium mobilization, inositol triphosphate production, and IL6 and CSF1 secretion. CD163 shedding produces a soluble form (sCD163) with potential anti-inflammatory properties, a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions. CD163 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD163 protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of CD163 Protein, Human (Biotinylated, HEK293, His-Avi) is 1004 a.a., with molecular weight of 120-140 kDa.

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