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Results for "

β-epoxide

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Biochemical Assay Reagents

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130502
    5β,6β-epoxycholestanol

    Cholesterol 5beta,6beta-epoxide

    		 Biochemical Assay Reagents Others
    5β,6β-epoxycholestanol is an oxidative metabolite of cholesterol formed by free-radical and non-radical oxidation of cholesterol at the 5,6 double bond. Induces lactate dehydrogenase (LDH) release and apoptosis in macrophage-differentiated U937 cells. Cholesterol 5beta,6beta-epoxide has been found in human fatty streaks and advanced atherosclerotic lesions, but not in normal aortic tissue .
    5β,6β-epoxycholestanol
  • HY-123349
    5α-Hydroxy-6-keto cholesterol

    		Drug Metabolite Cardiovascular Disease
    5α-Hydroxy-6-keto cholesterol is major metabolite of β-epoxide (5α,6β-epoxycholesterol) during direct exposure of intact cultured human bronchial epithelial cells (16-HBE) to ozone. 5α-Hydroxy-6-keto cholesterol inhibits cholesterol synthesis with an IC50 of 350 nM .
    5α-Hydroxy-6-keto cholesterol

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