β-gal

By Targets:	Amino Acid Derivatives (1) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (1) Endogenous Metabolite (2) Epigenetic Reader Domain (1) Fluorescent Dye (6) Glucosidase (1) NF-κB (1) PROTACs (1) TGF-beta/Smad (1)
By Research Areas:	Cancer (7) Infection (1) Inflammation/Immunology (2) Metabolic Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1878

*SPiDER-βGal-1*	Fluorescent Dye	Cancer
SPiDER-βGal-1 is a potent probe for β-galactosidase activity and suitable for labeling live cells in culture .

HY-W127769

Rose-β-D-Gal Salmon-gal	Fluorescent Dye	Others
Rose-β-D-Gal is a flurescent dye, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity .

HY-130570

β-Gal-NONOate	Bacterial	Infection Inflammation/Immunology
Beta-gal-nonoate is a β-galactosidase dependent nitric oxide (NO) donor that releases NO once activated by β-galactosidase. β-Gal-NONOate has bactericidal activity and can be used as a bactericide .

HY-E70299

*ST3 β-Gal* α-2,3-Sialyltransferase 5** ST3gal5	TGF-beta/Smad	Cancer
ST3 β-Gal α-2,3-Sialyltransferase 5 (ST3GAL5) is a glycosphingolipid (GSL) biosynthetic enzyme that can inhibit TGF-β-induced epithelial-mesenchymal transition (EMT), invasion, and metastasis both in vivo and in vitro. ST3 β-Gal α-2,3-Sialyltransferase 5 can be used in cancer research .

HY-E70298

*ST3 β-Gal* α-2,3-Sialyltransferase 1** ST3gal1	Endogenous Metabolite	Cancer
ST3 β-Gal α-2,3-Sialyltransferase 1 (ST3GAL1) is a sialyltransferase whose overexpression in ovarian cancer cell lines enhances cell growth, migration, and invasion capabilities, as well as increases tumorigenicity and resistance to paclitaxel in vivo. ST3 β-Gal α-2,3-Sialyltransferase 1 catalyzes the transfer of sialic acid from cytidine monophosphate-sialic acid to galactose-containing substrates and can be utilized in studies of cancer progression and chemotherapy resistance .

HY-N9134

5-O-Methylgenistein Isoprunetin	Glucosidase	Others
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits *β-gal* activityy induced by 17β-Estradiol (HY-B0141) in yeast .

HY-151890

*NIR-βgal-2*	Fluorescent Dye	Cancer
NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .

HY-D1879

*SPiDER-βGal-2*	Fluorescent Dye	Cancer
SPiDER-βGal-2 is a potent probe for β-galactosidase activity and suitable for labeling live cells in culture .

HY-132239

5-Bromo-6-chloro-3-indolyl β-D-Galactopyranoside contains ca. 10% Ethyl Acetate 5-Bromo-6-chloro-3-indolyl-beta-D-galactoside	Biochemical Assay Reagents	Others
5-Bromo-6-chloro-3-indolyl β-D-Galactopyranoside (contains ca. 10% Ethyl Acetate) (5-Bromo-6-chloro-3-indolyl-beta-D-galactoside) is a chromogenic substrate of β-galactosidase (β-gal) .

HY-124445

APC0576	NF-κB	Inflammation/Immunology
APC0576 is an inhibitor for the activation of NF-κB signaling pathway, and inhibits the activation of NF-κB depedent gene (IC₅₀ is 1.0 μM for β-gal). APC0576 inhibits IL-1-induced chemokines release, and can be used in research about pathological endothelial cell activation releted diseases .

HY-137276

5-Bromo-3-indolyl β-D-galactopyranoside Bluo-gal	Fluorescent Dye	Others
5-Bromo-3-indolyl β-D-galactopyranoside (Bluo-Gal) is a chromogenic substrate to detect bacterial β-D-galactosidase activity. 5-Bromo-3-indolyl β-D-galactopyranoside is used both to recognize labelled myofibers, and beta-gal positive organelles inside single myofibers .

HY-158331

Gal-ARV-771	PROTACs Epigenetic Reader Domain Apoptosis	Cancer
Gal-ARV-771, PROTAC prodrug, is a gal modified ARV-771 (HY-100972). Gal-ARV-771 can be activated in SA-β-Gal-expressed cancer senescent cells to release ARV-771. Gal-ARV-771 induces selective degradation of BRD4 protein by the ubiquitin-proteasome pathway in senescent cells. Gal-ARV-771 promotes apoptosis of senescent cancer cells .

HY-E70053

alpha-1,3-Galactosyltransferase (GTB) alpha 1,3GT	Endogenous Metabolite	Metabolic Disease
alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) catalyzes the synthesis of the xenoantigen or α-galactose (α-Gal) epitope. alpha-1,3-Galactosyltransferase (GTB) transfers galactose from UDP-Gal to type 1 or type 2, αFuc1→2βGal-R (H)-terminating acceptors .

HY-158742

SBB-Analogue (GL13) Biotin GL13; SBB-A-B	Fluorescent Dye	Others
SBB-Analogue (GL13) Biotin (GL13; SBB-A-B) is composed of a Sudan Black B (SBB; HY-D0213) derivative conjugated to biotin. SBB-Analogue (GL13) Biotin detects robustly senescent cells. SBB-Analogue (GL13) Biotin is deprived of the false positive staining disadvantages of SA-β-gal due to serum starvation and cell confluency. SBB-Analogue (GL13) Biotin can be used in flow cytometry and immunofluorescence analysis, etc .

HY-104004A

Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH Fmoc-Ser-(galNAc(Ac)3-beta-D)-OH; Fmoc-Ser[galNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-gal)-OH	Amino Acid Derivatives	Others
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .

Cat. No.	Product Name	Type

HY-D1878

*SPiDER-βGal-1*	Fluorescent Dyes/Probes
SPiDER-βGal-1 is a potent probe for β-galactosidase activity and suitable for labeling live cells in culture .

HY-W127769

Rose-β-D-Gal Salmon-gal	Fluorescent Dyes/Probes
Rose-β-D-Gal is a flurescent dye, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity .

HY-151890

*NIR-βgal-2*	Fluorescent Dyes/Probes
NIR-βgal-2 is a β-galactosidase-activated near-infrared fluorescent probe with superior sensitivity. NIR-βgal-2 can be used for visualizing β-galactosidase in breast cancer .

HY-D1879

*SPiDER-βGal-2*	Fluorescent Dyes/Probes
SPiDER-βGal-2 is a potent probe for β-galactosidase activity and suitable for labeling live cells in culture .

Cat. No.	Product Name	Type

HY-E70146

*ST3 β-Gal* α-2,3-Sialyltransferase 2** EC:2.4.3.4; ST3gal2	Enzyme Substrates
ST3 beta-Gal alpha-2,3-Sialyltransferase 2 (EC:2.4.3.4, ST3GAL2) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates .

HY-E70147

*ST3 β-Gal* α-2,3-Sialyltransferase 6** EC:2.4.99.; ST3gal6; Type 2 lactosamine α-2,3-sialyltransferase	Enzyme Substrates
ST3 beta-Gal alpha-2,3-Sialyltransferase 6 (EC:2.4.99., ST3GAL6; SIAT10, Type 2 lactosamine alpha-2,3-sialyltransferase) transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. ST3 beta-Gal alpha-2,3-Sialyltransferase 6 play an important role in cancer .

ST3 β-Gal α-2,3-Sialyltransferase 6

EC:2.4.99.; ST3gal6; Type 2 lactosamine α-2,3-sialyltransferase

Enzyme Substrates

ST3 beta-Gal alpha-2,3-Sialyltransferase 6 (EC:2.4.99., ST3GAL6; SIAT10, Type 2 lactosamine alpha-2,3-sialyltransferase) transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. ST3 beta-Gal alpha-2,3-Sialyltransferase 6 play an important role in cancer .

Cat. No.	Product Name	Target	Research Area

HY-104004A

Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH Fmoc-Ser-(galNAc(Ac)3-beta-D)-OH; Fmoc-Ser[galNAc(Ac)3-β-D]-OH; Fmoc-Ser(Ac3AcNH-β-gal)-OH	Amino Acid Derivatives	Others
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a serine derivative .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N9134

5-O-Methylgenistein Isoprunetin	Structural Classification Flavonoids Leguminosae Source classification Maackia amurensis Rupr. et Maxim. Plants Isoflavones	Glucosidase
5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits *β-gal* activityy induced by 17β-Estradiol (HY-B0141) in yeast .

Cat. No.	Compare	Product Name	Species	Source

HY-P7859

	Beta-galactosidase/GLB1 Protein, E.coli rEcoBeta-galactosidase; Beta-galactosidase; Beta-gal; Lactase; lacZ	E.coli	E. coli
	Beta-galactosidase/GLB1 protein is a hydrolase with catalytic activity and binding sites of Mg²⁺, Mn²⁺ and Na⁺. Beta-galactosidase/GLB1 protein can be used for research in genetics, molecular biology, and other life sciences. Beta-galactosidase/GLB1 Protein, E.coli is the recombinant E. coli-derived Beta-galactosidase/GLB1 protein, expressed by E. coli , with tag free.

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