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Results for "

1,2,4-oxadiazoles

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-144634
    DDO-7263

    		Keap1-Nrf2 Neurological Disease Inflammation/Immunology
    DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2-ARE activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 induces Nrf2 translocation into the nucleus. DDO-7263 inhibits of NLRP3 inflammasome activation. DDO-7263 exerts anti-inflammatory activity and has the potential for neurodegenerative diseases research, such as Parkinson's disease (PD) .
    DDO-7263
  • HY-146753
    HIV-1 inhibitor-20

    		HIV Infection
    HIV-1 inhibitor-20 is a potent HIV-1 inhibitor by non-classical isosteric replacement of amide to 1,2,4-oxadiazoles .
    HIV-1 inhibitor-20
  • HY-143242
    Phidianidine B

    		Others Others
    Phidianidine B is a highly cytotoxic 1,2,4-oxadiazole marine metabolite. Phidianidine B is a natural product that can be isolated from a marine mollusk .
    Phidianidine B
  • HY-W190972
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole

    		Others Others
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole is a PEG derivative containing a tert-butyl ester and an azide group .
    3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole
  • HY-P10472
    Azaline B

    		GnRH Receptor Endocrinology
    Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
    Azaline B

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