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Results for "

15-Keto Bimatoprost

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132277S
    15-Keto Bimatoprost-d5

    		Isotope-Labeled Compounds Others
    15-Keto Bimatoprost-d5 is the deuterium labeled 15-Keto Bimatoprost. 15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive[1][2].
    15-Keto Bimatoprost-d5
  • HY-132277
    15-Keto Bimatoprost

    		Others Endocrinology
    15-Keto Bimatoprost is a prostaglandin F2α (PGF2α) analog that can be used for the research of ocular hypotensive .
    15-Keto Bimatoprost
  • HY-113778
    15-keto-17-phenyl trinor Prostaglandin F2α

    15-Keto-17-phenyl trinor PGF2α

    		 Prostaglandin Receptor Endocrinology
    Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug.1 Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compound, 15-keto PGs still retain the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye.2 15-keto Latanoprost (15-keto-17-phenyl-13,14-dihydro trinor PGF2α isopropyl ester) is a miotic in the normal cat eye, causing an 8 mm reduction in pupillary diameter at 5 μg/eye. Again, this is not as potent as many other F-type PGs; for example, PGF2α will produce this degree of miosis at a dose of less than 1 μg/eye.
    15-keto-17-phenyl trinor Prostaglandin F2α

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