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Results for "

ADV

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14532
    Brincidofovir
    2 Publications Verification

    CMX001; HDP-CDV

    		 CMV HSV Orthopoxvirus Infection
    Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .
    Brincidofovir
  • HY-129477
    Strictamine

    		HSV Infection
    Strictamine (compound 2) is an alkaloid with antiviral activity. Strictamine has significant inhibitory activity against herpes simplex virus (HSV) and adenovirus (ADV), with EC50 values ??of 0.36 μg/mL and 0.28 μg/mL, respectively .
    Strictamine
  • HY-P5694
    Human α-defensin 5

    		HPV Parasite Infection
    Human α-defensin 5 is an antiviral peptide. Human α-defensin 5 blocks infection of non-enveloped viruses, including AdV, HPV, and polyomaviruses (IC50: 0.6-1.25 μM for HPV16). Human α-defensin 5 can bind to the viral capsid and blocks escape of the virus from the endosome. Human α-defensin 5 increases HIV binding to the cell surface. Human α-defensin 5 also has parasiticidal activity .
    Human α-defensin 5
  • HY-114784
    Ingavirin

    Ingamine

    		 Influenza Virus Infection
    Ingavirin (Ingamine) exhibits broad spectrum antiviral activities against human respiratory viruses, such as influenza virus A (IVA), human parainfluenza virus (hPIV) and human adenovirus (AdV). Ingavirin exhibits no toxixcity to mice at the dose of 3000 mg/kg .
    Ingavirin
  • HY-149900
    Antiviral agent 33

    		Biochemical Assay Reagents Infection
    Antiviral agent 33 (compound 1c) is a double-stranded DNA (dsDNA) virus inhibitor with IC50 values of 0.0790 and 0.1572 µM for VACV and AdV5, respectively. Antiviral agent 33 also has potential for oral administration .
    Antiviral agent 33
  • HY-155823
    TZ4M

    		Cholinesterase (ChE) Neurological Disease
    TZ4M is a 2,4-thiazolidinedione (TZD)-based anti-ADV agent with neuroprotective effects. TZ4M exhibits AChE inhibition in human plasma. TZ4M improves memory and cognitive impairment in adult rats in a scopolamine (HY-N0296)-induced Alzheimer-type model .
    TZ4M

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