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ASP 3026

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13326
    ASP3026
    5 Publications Verification

    Anaplastic lymphoma kinase (ALK) Apoptosis ROS Kinase Caspase PARP IGF-1R STAT Akt JNK Cancer
    ASP3026 is a selective and orally active inhibitor of anaplastic lymphoma kinase (ALK). ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK. ASP3026 can be used in anti-tumor research .
    ASP3026
  • HY-161799

    Aminoacyl-tRNA Synthetase Parasite Infection
    LysRs-IN-3 (compound 36) is an inhibitor of Plasmodium lysine tRNA synthetase based on ASP3026 (HY-13326), which has a more than seven-fold higher inhibitory effect on the growth of Plasmodium, especially Plasmodium falciparum, than ASP3026 (HY-13326). LysRs-IN-3 can be used in the development of antimalarial drugs .
    LysRs-IN-3

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