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By Targets:	Antibody-Drug Conjugates (ADCs) (1)
By Research Areas:	Cancer (1)

Azintuxizumab vedotin ABBV-838	Antibody-Drug Conjugates (ADCs)	Cancer
Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells .

Azintuxizumab vedotin ABBV-838	Antibody-Drug Conjugates (ADCs)	Cancer
Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells .

Species:	Human (7) Rhesus Macaque (1) Mouse (1)
Tag:	His (6) Avi (2) Fc (3)
Source:	HEK293 (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P72460

	CRACC/SLAMF7 Protein, Human (HEK293, His) SLAM Family Member 7; CD2 Subset 1; CRACC; CD319; SLAMF7; CS1	Human	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. CRACC/SLAMF7 Protein, Human (HEK293, His) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72461

	CRACC/SLAMF7 Protein, Mouse (HEK293, His) SLAM Family Member 7; CD2 Subset 1; CRACC; CD319; SLAMF7; CS1	Mouse	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that critically regulates immune cell activation and differentiation through homotypic or heterotypic interactions. It coordinates distinct immune responses, dependent on the presence or absence of the cytoplasmic linkers SH2D1A/SAP and/or SH2D1B/EAT-2. CRACC/SLAMF7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77202

	CRACC/SLAMF7 Protein, Human (HEK293, hFc) SLAM Family Member 7; CD2 Subset 1; CRACC; CD319; SLAMF7; CS1	Human	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. CRACC/SLAMF7 Protein, Human (HEK293, hFc) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77203

	CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, Fc) SLAM Family Member 7; CD2 Subset 1; CRACC; CD319; SLAMF7; CS1	Human	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77205

	CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His) SLAM Family Member 7; CD2 Subset 1; CRACC; CD319; SLAMF7; CS1	Human	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-His labeled tag.

HY-P72416

	CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His-Avi) CD2 Subset 1; CRACC; Membrane Protein FOAP-12; Novel Ly9; Protein 19A; CD319; CS1	Human	HEK293
	The FITC-labeled CRACC/SLAMF7 protein, a self-ligand receptor in the SLAM family, intricately regulates immune cell activation and differentiation through finely tuned interactions. Isoform 1 mediates NK cell activation via a SH2D1A-independent ERK-mediated pathway, positively regulating NK cell functions dependent on phosphorylated SH2D1B. It inhibits NK cell function in the absence of SH2D1B and acts as an inhibitory factor in T-cells. In LPS-activated monocytes, it negatively regulates pro-inflammatory cytokine production. However, isoform 3 shows no NK cell activation, suggesting isoform-specific immune modulation. CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of CRACC/SLAMF7 Protein, Human (Biotinylated, HEK293, His-Avi) is 204 a.a., with molecular weight of 35-55 kDa.

HY-P78517

	CRACC/SLAMF7 Protein, Human (HEK293, mFc) CD2 subset 1; CRACC; Novel Ly9; CD319; SLAMF7; CS1; 19A; FOAP-12	Human	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. CRACC/SLAMF7 Protein, Human (HEK293, mFc) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P78518

	CRACC/SLAMF7 Protein, Human (HEK293, His-Avi) CD2 subset 1; CRACC; Novel Ly9; CD319; SLAMF7; CS1; 19A; FOAP-12	Human	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that complexly regulates immune cell activation and differentiation through finely regulated interactions. Isoform 1 mediates NK cell activation through an SH2D1A-independent ERK-mediated pathway and positively regulates NK cell function dependent on phosphorylated SH2D1B. CRACC/SLAMF7 Protein, Human (HEK293, His-Avi) is the recombinant human-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P72770

	CRACC/SLAMF7 Protein, Rhesus Macaque (HEK293, His) SLAM Family Member 7; CD2 Subset 1; CD2-Like Receptor-Activating Cytotoxic Cells; CRACC; Membrane Protein FOAP-12; Novel Ly9; Protein 19A; CD319; SLAMF7; CS1	Rhesus Macaque	HEK293
	The CRACC/SLAMF7 protein is an autoligand receptor in the SLAM family that critically regulates immune cell activation and differentiation through homotypic or heterotypic interactions. It coordinates distinct immune responses, dependent on the presence or absence of the cytoplasmic linkers SH2D1A/SAP and/or SH2D1B/EAT-2. CRACC/SLAMF7 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CRACC/SLAMF7 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRACC/SLAMF7 Protein, Rhesus Macaque (HEK293, His) is 204 a.a., with molecular weight of 30-50 kDa.

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