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DHICA

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W018158

    5,6-Dihydroxyindole-2-carboxylic acid

    Endogenous Metabolite GPR35 Arrestin Others
    DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an intermediate in melanin synthesis and a component of true black pigment, and it’s also a moderately potent GPR35 agonist. DHICA shows an ability to stimulate β-arrestin translocation signaling with an EC50 value of 23.2 μM in the U2OS cell line. DHICA plays a significant role in promoting and protecting against DNA damage .
    DHICA

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