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Dealanylalahopcin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) HIF/HIF Prolyl-Hydroxylase (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Dealanylalahopcin*	Bacterial	Infection
Dealanylalahopcin is an antimicrobial agent that can be isolated from the culture filtrate of Streptomyces leucoderma subsp. ochraceus. Dealanylalahopcin can also be synthesized by enzymatic hydrolysis of alahopcin by microbial α-amino acid ester hydrolases. Dealanylalahopcin has weak antimicrobial activity against Gram-positive and Gram-negative bacteria and exhibits moderate inhibition of collagen prolyl hydroxylase .

*FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2*	HIF/HIF Prolyl-Hydroxylase	Cancer
FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2, a 5-FAM labeled HIF-1α peptide, is a substrate of VHL. FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2 binds to VHL protein with a K_D of 3 nM. Ex/Em (λ) = 485/520 nm .

Cat. No.	Product Name	Target	Research Area

DEALA-Hyp-YIPD	Peptides	Cardiovascular Disease
DEALA-Hyp-YIPD is an HIF-1α peptide that inhibits VHL/HIF-1α interaction with an IC₅₀ of 0.91 μM and a K_d of 180 nM .

*FAM-DEALA-Hyp-YIPD*	Peptides	Others
FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide, with the K_d of 180-560 nM. FAM-DEALA-Hyp-YIPD can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity .

*FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2*	HIF/HIF Prolyl-Hydroxylase	Cancer
FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2, a 5-FAM labeled HIF-1α peptide, is a substrate of VHL. FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2 binds to VHL protein with a K_D of 3 nM. Ex/Em (λ) = 485/520 nm .

Cat. No.	Product Name	Category	Target	Chemical Structure

*Dealanylalahopcin*	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial
Dealanylalahopcin is an antimicrobial agent that can be isolated from the culture filtrate of Streptomyces leucoderma subsp. ochraceus. Dealanylalahopcin can also be synthesized by enzymatic hydrolysis of alahopcin by microbial α-amino acid ester hydrolases. Dealanylalahopcin has weak antimicrobial activity against Gram-positive and Gram-negative bacteria and exhibits moderate inhibition of collagen prolyl hydroxylase .

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