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Results for "

ECE-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Fluorescent Dye

1

Peptides

1

Natural
Products

1

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N11772
    Mutanocyclin

    		Fungal Infection
    Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse [1].
    Mutanocyclin
  • HY-P3749
    Mca-(ala7,lys(dnp)9)-bradykinin

    		Fluorescent Dye Others
    Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage [1].
    Mca-(ala7,lys(dnp)9)-bradykinin
  • HY-RS04133
    ECE1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ECE1 Human Pre-designed siRNA Set A contains three designed siRNAs for ECE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ECE1 Human Pre-designed siRNA Set A
    ECE1 Human Pre-designed siRNA Set A
  • HY-107762
    CGS35066

    		Others Cardiovascular Disease
    CGS35066 is a potent and selective aminophosphonate inhibitor of endothelin-converting enzyme-1 (ECE-1). CGS 35066 inhibits the activity of human ECE-1 and rat kidney neutral endopeptidase 24.11 (NEP) in vitro with IC50 values of 22 nM and 2.3 μM, respectively [1].
    CGS35066
  • HY-119545
    PD159790

    		Others Cardiovascular Disease
    PD159790 is a selective endothelin-converting enzyme-1 (ECE-1) inhibitor, with an EC50 of 28.1 μM [1] .
    PD159790
  • HY-18211
    CGS 35601

    		Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    CGS 35601 is the inhibitor for endothelin-converting enzyme-1 (ECE-1), neutral endopeptidase 24.11 (NEP), and angiotensin-converting enzyme (ACE), with IC50s of 55, 2, and 22 nM, respectively. CGS 35601 suppresses the big endothelin-1 (big ET-1)- and angiotensin I-induced pressor response, and enhances circulation of atrial natriuretic peptide (ANP), regulates the cardiovascular function in SD rats [1].
    CGS 35601

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