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EGFR-IN-137

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-169408
    EGFR-IN-137

    		Cytochrome P450 EGFR Apoptosis Cancer
    EGFR-IN-137 (Compound 4c) is an inhibitor for aromatase and EGFR with IC50s of 1.67 μg/mL and 0.08 μg/mL. EGFR-IN-137 inhibits the proliferation of cancer cell MCF-7 and MDA-MB-231 with IC50s of 1.62 µM and 4.14 µM. EGFR-IN-137 arrests the cell cycle at G0/G1 phase in MDA-MB-231, and induces apoptosis through caspase-dependent pathway .
    EGFR-IN-137

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