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Results for "

GD2

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

4

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99757
    Nivatrotamab

    Hu3F8-BsAb

    		 CD2 CD3 Cancer
    Nivatrotamab (Hu3F8-BsAb) is a humanized anti-GD2/CD3 bispecific antibody. Nivatrotamab is a CD3- and GD2-specific bsAb-based T-cell engager. Nivatrotamab can be used in research of neuroblastoma .
    Nivatrotamab
  • HY-E70049
    beta-1,4-N-Acetylgalactosaminyltransferase (CgtA)

    GM2/GD2 synthase

    		 Others Neurological Disease
    beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides .
    beta-1,4-N-Acetylgalactosaminyltransferase (CgtA)
  • HY-158109
    M3554

    		Others Cancer
    M3554 is a novel anti-GD2 ADC designed based on humanized ch14.18 anti-GD2 antibody and has anti-tumor activity. The cytotoxicity of M3554 against the GD2-positive neuroblastoma cell line CHP134 was in the subnanomolar IC50 range.
    M3554

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