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Results for "

Leptomycin B

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

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Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16909
    Leptomycin B
    5+ Cited Publications

    CI 940; LMB

    		 CRM1 Fungal Antibiotic Infection Cancer
    Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle .
    Leptomycin B
  • HY-164710
    Biotinylated leptomycin B

    		Others Others
    Biotinylated leptomycin B is a compound used to quantify nuclear export protein 1 (XPO1) occupancy and is used to study the interaction of SINE compounds with XPO1 and the response of cancer cells to related compounds.
    Biotinylated leptomycin B
  • HY-N6795
    Leptomycin A

    		CRM1 HIV Antibiotic Infection
    Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B .
    Leptomycin A

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