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Lipopolysaccharides, from S. enterica serotype minnesota

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By Targets:	Toll-like Receptor (TLR) (1)
By Research Areas:	Inflammation/Immunology (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1056C2

**Lipopolysaccharides, from S. enterica serotype minnesota** LPS, from Salmonella enterica (serotype minnesota)	Toll-like Receptor (TLR)	Inflammation/Immunology
Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

Cat. No.	Product Name	Type

HY-D1056C2

**Lipopolysaccharides, from S. enterica serotype minnesota** LPS, from Salmonella enterica (serotype minnesota)	Carbohydrates
Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

Lipopolysaccharides, from S. enterica serotype minnesota

LPS, from Salmonella enterica (serotype minnesota)

Carbohydrates

Lipopolysaccharides (LPS) are specific endotoxins and one of the major components of the cell wall of Gram-negative bacteria. Lipopolysaccharides consist of three parts: lipid A, core oligosaccharide, and O-specific polysaccharide. Lipopolysaccharides are powerful immune stimulants that can activate the host immune system, particularly by binding to Toll-like receptor 4 (TLR4) on the surface of immune cells, triggering an inflammatory response. The LPS of most Salmonella serotypes has a complex O-antigen (OAg) structure, with the number of OAg units in the core polysaccharide varying between 16 and over 100 repeats. Mutations in OAg-regulating factors that alter the OAg structure can change the interaction between Salmonella and epithelial cells. Strains with long OAg have increased SPI1-T3SS effector protein translocation and invasion. Strains completely lacking OAg exhibit increased invasiveness and higher adhesiveness. This product is derived from Salmonella enterica serotype Minnesota. Lipopolysaccharides, from S. enterica serotype minnesota, can be used to study host immune system activation and its role in inflammation and immune regulation .

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