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Results for "

MLV

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124871
    LASV inhibitor 3.3

    		Arenavirus Infection
    LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research .
    LASV inhibitor 3.3
  • HY-100159
    Ipenoxazone

    MLV-6976; NC-1200

    		 Others Neurological Disease
    Ipenoxazone is a potent and centrally acting muscle relaxant.
    Ipenoxazone
  • HY-131161
    M-MLV Reverse transcriptase

    M-MLV RT

    		 Reverse Transcriptase Infection
    M-MLV Reverse transcriptase (M-MLV RT) is a kind of Reverse transcriptase, from the moroni mouse leukemia virus (MoMLV) .
    M-<em>MLV</em> Reverse transcriptase
  • HY-160924
    MS147

    		PROTACs E1/E2/E3 Enzyme Cancer
    MS147 is a VHL-based PROTAC degrader of PRC1 (Polycomb Repressive Complex 1). The dissociation constants (Kd) of MS147 for EED (Embryonic Ectoderm Development) and VHL (Von Hippel-Lindau) are 3.0 μM and 450 nM, respectively. MS147 specifically binds to the EED protein through its EED-binding moiety; EED is a core component of PRC2 (Polycomb Repressive Complex 2) and interacts with the core components of PRC1, BMI1 (B-lymphoma Mo-MLV insertion region 1 homolog) and RING1B (Ring Finger Protein 1B). By this binding, MS147 is able to recruit BMI1 and RING1B near to VHL. Through the degradation of BMI1 and RING1B, MS147 reduces the level of H2AK119ub (histone H2A lysine 119 ubiquitination), affecting the proliferation of cancer cells. (Blue: VHL ligand (HY-125845), Black: linker ; Pink: PRC1 ligand (HY-158771)) .
    MS147

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