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Results for "

MPI

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Cathepsin (1) HDAC (1) Mps1 (1) PGE synthase (1) SARS-CoV (4) Small Interfering RNA (siRNA) (1) Virus Protease (1)
By Research Areas:	Cancer (3) Infection (5) Metabolic Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Recombinant Proteins

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113957

MPI_5a	HDAC	Cancer
MPI_5a is a potent and selective HDAC6 inhibitor (IC₅₀=36 nM). MPI_5a weakly inhibits other HDAC isoforms. MPI_5a inhibits acyl-tubulin accumulation in cells with an IC₅₀ value of 210 nM .

HY-12660

MPI-0479605 3 Publications Verification	Mps1 Apoptosis	Cancer
MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC₅₀ of 1.8 nM.

HY-112945

MLS0315771 2 Publications Verification	Others	Metabolic Disease
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase *(MPI)* inhibitor, with an IC₅₀ ~1 μM and a K_i of 1.4 μM.

HY-147416

Vipoglanstat BI 1029539; GS-248; OX-MPI	PGE synthase	Infection
Vipoglanstat (BI 1029539), a carboxamide, is a potent and selective, non-peptide and orally active small molecular inhibitor of human prostaglandin E synthase 1 (mPGES-1). Vipoglanstat also has anti-inflammatory activity .

HY-129715

MPI-0441138	Apoptosis	Cancer
MPI-0441138 is an inducer of apoptosis and an inhibitor of mitosis. MPI-0441138 can induce DNA breaks and induce cytochrome c translocation, leading to tumor cell death .

HY-155813

MPI60	SARS-CoV	Infection
MPI60 is a potent SARS-CoV-2 M ^Pro inhibitor with high antiviral potency, low cellular cytotoxicity, and high in vitro metabolic stability. MPI60 can be used for SARS-CoV-2 research .

HY-158763

MPI8 TG0205221	SARS-CoV Cathepsin Virus Protease	Infection
MPI8 (TG0205221) is an inhibitor of the major protease of SARS-CoV-2 (MPro) with high antiviral activity. MPI8 exerts its antiviral effect by dual and selective inhibition of SARS-CoV-2 MPro and host cell cysteine protease L (cathepsin L). This dual inhibition enhanced the overall antiviral potency and effect of MPI8. MPI8 can be used in clinical studies of COVID-19 .

HY-RS08614

MPI Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MPI Human Pre-designed siRNA Set A contains three designed siRNAs for MPI gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MPI Human Pre-designed siRNA Set A MPI Human Pre-designed siRNA Set A

HY-163628

SARS-CoV-2 Mpro-IN-20	SARS-CoV	Infection
SARS-CoV-2 Mpro-IN-20 (compound MPI100) is a SARS-CoV-2 main protease inhibitor. SARS-CoV-2 Mpro-IN-20 shows antiviral activity with the EC₅₀ of 3.4 μM .

HY-163627

SARS-CoV-2 Mpro-IN-19	SARS-CoV	Infection
SARS-CoV-2 Mpro-IN-19 (compound MPI94) is a SARS-CoV-2 MPro inhibitor with the IC₅₀ of 0.096 μM. SARS-CoV-2 Mpro-IN-19 can be used for study of COVID-19 .

Species:	Human (3) Mouse (1)
Tag:	His (2) Fc (2)
Source:	HEK293 (2) Sf9 insect cells (1) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P73414

	SLPI Protein, Human (107a.a, Sf9, His) Antileukoproteinase; ALP; BLPI; SLPI; MPI; WAP4; WFDC4	Human	Sf9 insect cells
	The SLPI protein is an acid-stable protease inhibitor that has shown strong affinity for trypsin, chymotrypsin, elastase, and cathepsin G in multiple studies. It plays a critical regulatory role in inflammatory and immune responses following bacterial infection and Listeria monocytogenes infection. SLPI Protein, Human (107a.a, Sf9, His) is the recombinant human-derived SLPI protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of SLPI Protein, Human (107a.a, Sf9, His) is 107 a.a., with molecular weight of ~19 kDa.

HY-P78041

	SLPI Protein, Mouse (HEK293, Fc) ALP; BLPI; HUSI-1; MPI; WAP4; WFDC4; ALK1; HUSI; SLPI	Mouse	HEK293
	The SLPI protein is an acid-stable protease inhibitor that modulates immune responses to bacterial infections.It downregulates responses to bacterial lipopolysaccharide (LPS) and modulates NF-kappa-B activation and inflammatory responses.SLPI Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived SLPI protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73414A

	SLPI Protein, Human (107a.a, sf9, His, solution) Antileukoproteinase; ALP; BLPI; SLPI; MPI; WAP4; WFDC4	Human	Sf9 insect cells
	SLPI Protein, an acid-stable proteinase inhibitor, demonstrates strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G in various studies. It crucially modulates inflammatory and immune responses post-bacterial infection and L.major infection. SLPI down-regulates responses to bacterial lipopolysaccharide (LPS), regulates NF-kappa-B activation, impacting inflammatory responses. It exhibits antimicrobial activity against mycobacteria, contributing to resistance against M.tuberculosis. Essential for normal resistance to L.major infection, SLPI plays a vital role in wound healing, preventing tissue damage by regulating protease activity. Collaborating with ELANE, SLPI is necessary for normal bone marrow myeloid cell differentiation and proliferation, interacting with GRN to protect progranulin from proteolysis. SLPI Protein, Human (107a.a, sf9, His, solution) is the recombinant human-derived SLPI protein, expressed by Sf9 insect cells, with N-6*His labeled tag. The total length of SLPI Protein, Human (107a.a, sf9, His, solution) is 107 a.a., with molecular weight of ~19 kDa.

HY-P78548

	SLPI Protein, Human (HEK293, Fc) ALP; BLPI; HUSI-1; MPI; WAP4; WFDC4; ALK1; HUSI; SLPI	Human	HEK293
	SLPI Protein, an acid-stable proteinase inhibitor, demonstrates strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G in various studies. It crucially modulates inflammatory and immune responses post-bacterial infection and L.major infection. SLPI down-regulates responses to bacterial lipopolysaccharide (LPS), regulates NF-kappa-B activation, impacting inflammatory responses. It exhibits antimicrobial activity against mycobacteria, contributing to resistance against M.tuberculosis. Essential for normal resistance to L.major infection, SLPI plays a vital role in wound healing, preventing tissue damage by regulating protease activity. Collaborating with ELANE, SLPI is necessary for normal bone marrow myeloid cell differentiation and proliferation, interacting with GRN to protect progranulin from proteolysis. SLPI Protein, Human (HEK293, Fc) is the recombinant human-derived SLPI protein, expressed by HEK293, with C-hFc labeled tag. The total length of SLPI Protein, Human (HEK293, Fc) is 107 a.a., with molecular weight of 40-50 kDa.

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MPI Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
MPI Human Pre-designed siRNA Set A contains three designed siRNAs for MPI gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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