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Results for "

Micheliolide

" in MedChemExpress (MCE) Product Catalog:

2

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2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0847
    Micheliolide
    4 Publications Verification

    		 NF-κB PI3K Akt TGF-beta/Smad Inflammation/Immunology Cancer
    Micheliolide is a sesquiterpene lactone with anti-cancer and anti-inflammatory effects, which is derived from Michelia compressa and Michelia champaca. Micheliolide can attenuate high glucose-stimulated NF-κB activation, IκBα degradation, and the expression of MCP-1, TGF-β1, and FN in mouse mesangial cells. Micheliolide inhibits LPS (HY-D1056)-induced activation of NF-κB and PI3K/Akt/p70S6K pathways to play an anti-inflammatory role. Micheliolide inhibits dextran sodium sulphate (DSS) (HY-116282)-induced inflammatory intestinal disease, colitis-associated cancer and rheumatic arthritis .
    Micheliolide
  • HY-N0845
    Epoxymicheliolide

    1β,10β-EpoxyMicheliolide

    		 Others Inflammation/Immunology
    Epoxymicheliolide is a micheliolide derivative.
    Epoxymicheliolide

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