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Results for "

Pilocarpine

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

3

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0726A
    Pilocarpine
    Maximum Cited Publications
    22 Publications Verification

    		 mAChR Neurological Disease
    Pilocarpine is a selective M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    <em>Pilocarpine</em>
  • HY-B0726
    Pilocarpine Hydrochloride
    Maximum Cited Publications
    22 Publications Verification

    		 mAChR Neurological Disease Cancer
    Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    <em>Pilocarpine</em> Hydrochloride
  • HY-B0726S
    Pilocarpine-d3 hydrochloride

    		Isotope-Labeled Compounds mAChR Neurological Disease
    Pilocarpine-d3 (hydrochloride) is deuterium labeled Pilocarpine (Hydrochloride). Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    <em>Pilocarpine</em>-d3 hydrochloride
  • HY-B0726S1
    Pilocarpine-d5 hydrochloride

    		mAChR Isotope-Labeled Compounds Neurological Disease Cancer
    Pilocarpine-d5 hydrochloride is deuterated labeled Pilocarpine hydrochloride (HY-B0726). Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    <em>Pilocarpine</em>-d5 hydrochloride
  • HY-B1006R
    Pilocarpine nitrate (Standard)

    		mAChR Neurological Disease Cancer
    Pilocarpine (nitrate) (Standard) is the analytical standard of Pilocarpine (nitrate). This product is intended for research and analytical applications. Pilocarpine nitrate is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    <em>Pilocarpine</em> nitrate (Standard)
  • HY-B1006
    Pilocarpine nitrate
    Maximum Cited Publications
    22 Publications Verification

    		 mAChR Neurological Disease Cancer
    Pilocarpine nitrate is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
    <em>Pilocarpine</em> nitrate
  • HY-103232
    IEM-1925 bromide

    		mGluR Neurological Disease
    IEM-1925 bromide is an orally active glutamate receptor antagonist, increases the latent period and decreases the duration of status epilepticus in rats in a lithium-pilocarpine model of epilepsy .
    IEM-1925 bromide
  • HY-100265
    Cinperene

    R5046

    		 Others Neurological Disease
    Cinperene is an atropine-like agent which can block pilocarpine-induced lacrimation and salivation.
    Cinperene
  • HY-108234
    VU 0255035

    VU 255035

    		 mAChR Neurological Disease
    VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM. VU 0255035 reduces pilocarpine-induced seizures in mice. VU0255035 is used to examine the role of the M1 receptor in diverse situations .
    VU 0255035
  • HY-149422
    NIR-FP

    		Fluorescent Dye Neurological Disease
    NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O 2-. O 2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O 2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model .
    NIR-FP
  • HY-164049
    TG8-260

    		Prostaglandin Receptor Inflammation/Immunology
    TG8-260 is a second-generation EP2 antagonist developed to alleviate the pathology of central nervous system and peripheral diseases driven by inflammation. TG8-260 can reduce neuroinflammation and gliosis in the hippocampus of rats after pilocarpine-induced persistent epileptic status. Pharmacokinetic data of TG8-260 showed that its plasma half-life was 2.14 hours and its oral bioavailability was 77.3%. TG8-260 is also a potent inhibitor of CYP450 and shows antagonistic activity in inhibiting EP2 receptor-mediated inflammatory gene expression in BV2-hEP2 microglia, which is suitable for studying anti-inflammatory pathways in animal models of peripheral inflammatory diseases .
    TG8-260

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