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Results for "

REV1

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126214
    JH-RE-06
    1 Publications Verification

    		 DNA/RNA Synthesis Cancer
    JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy [1] .
    JH-RE-06
  • HY-RS11861
    REV1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    REV1 Human Pre-designed siRNA Set A contains three designed siRNAs for REV1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    REV1 Human Pre-designed siRNA Set A
    REV1 Human Pre-designed siRNA Set A
  • HY-117846
    MLAF50

    		DNA/RNA Synthesis Cancer
    MLAF50 is apotent REV1 UBM2-Ubiquitin interaction inhibitor. MLAF50 inhibits chromatin co-localization of REV1 with PCNA following DNA-damage induction [1].
    MLAF50
  • HY-126214S
    JH-RE-06-d6

    		DNA/RNA Synthesis Cancer
    JH-RE-06-d6 is deuterium labele JH-RE-06. JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Ki=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy [1].
    JH-RE-06-d6

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