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Results for "

RRM1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153736
    NSC 194308

    		Others Cancer
    NSC 194308, a U2AF2-RNA complexes enhancer, increases association of the U2AF1-U2AF2-SF1-splice site RNA complex by binding a site between the U2AF2 RNA recognition motifs (RRM1 and RRM2). NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell death in leukemia cell lines containing spliceosome mutations [1].
    NSC 194308
  • HY-153898
    rTRD01

    		Others Neurological Disease
    rTRD01 is a TDP-43 ligand that binds to TDP-43’s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102–269). rTRD01 partially disrupts TDP-43’s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases [1].
    rTRD01
  • HY-RS12285
    RRM1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    RRM1 Human Pre-designed siRNA Set A contains three designed siRNAs for RRM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    RRM1 Human Pre-designed siRNA Set A
    RRM1 Human Pre-designed siRNA Set A

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