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  3. Enzymes & Regulators
  4. Oxidoreductases (EC 1)
  5. RRM1 Protein, Human (sf9, His-GST)

RRM1 Protein, Human (sf9, His-GST)

Cat. No.: HY-P74591
Handling Instructions

RRM1 Protein, crucial for DNA synthesis, catalyzes the biosynthesis of deoxyribonucleotides from ribonucleotide precursors. Its enzymatic activity is essential, providing building blocks for accurate and efficient DNA replication. RRM1 Protein, Human (sf9, His-GST) is the recombinant human-derived RRM1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of RRM1 Protein, Human (sf9, His-GST) is 792 a.a., with molecular weight of ~98 kDa.

For research use only. We do not sell to patients.

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Description

RRM1 Protein, crucial for DNA synthesis, catalyzes the biosynthesis of deoxyribonucleotides from ribonucleotide precursors. Its enzymatic activity is essential, providing building blocks for accurate and efficient DNA replication. RRM1 Protein, Human (sf9, His-GST) is the recombinant human-derived RRM1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of RRM1 Protein, Human (sf9, His-GST) is 792 a.a., with molecular weight of ~98 kDa.
Background

The RRM1 protein serves a crucial role in DNA synthesis by catalyzing the biosynthesis of deoxyribonucleotides from their corresponding ribonucleotide precursors. This enzymatic activity is essential for providing the necessary building blocks required for the intricate process of DNA replication, ensuring the accurate and efficient synthesis of new DNA strands.
Species

Human
Source

Sf9 insect cells
Tag

N-His;N-GST
Accession

P23921 (M1-S792)
Gene ID
Molecular Construction
N-term
His-GST
RRM1 (M1-S792)
Accession # P23921
C-term
Synonyms
Ribonucleoside-diphosphate reductase large subunit; RRM1; RR1
Molecular Weight

Approximately 98 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

RRM1 Protein, Human (sf9, His-GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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