Search Result

Results for "

SH group

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Drug-Linker Conjugates for ADC (1) FAAH (1) Fluorescent Dye (3) Liposome (1) Monoamine Oxidase (1) PROTAC Linkers (4) Radionuclide-Drug Conjugates (RDCs) (1)
By Research Areas:	Cancer (6) Inflammation/Immunology (1) Neurological Disease (1)
Click Chemistry:	PROTAC Synthesis (4) Alkynes (5)
Oligonucleotides:	Pegylated Lipids (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D2381

AF 488 maleimide	Fluorescent Dye	Others
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-W087027

Maleimide-NOTA	Radionuclide-Drug Conjugates (RDCs)	Cancer
Maleimide-NOTA is a chelator for the labeling of peptides and antibodies. Maleimide-NOTA can react with cysteine .

HY-130900

Propargyl-PEG3-SH	PROTAC Linkers	Cancer
Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135917

Propargyl-PEG6-SH	PROTAC Linkers	Cancer
Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130910

Propargyl-PEG8-SH	PROTAC Linkers	Cancer
Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG8-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130911

Propargyl-PEG12-SH	PROTAC Linkers	Cancer
Propargyl-PEG12-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG12-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135133

S-Phenylsulfonylcysteine	Biochemical Assay Reagents	Others
S-Phenylsulfonylcysteine is a reagent for blocking thiol (-SH) groups on proteins and peptides .

HY-139143

WWL154	FAAH	Others
WWL154, an analog of JZL184 that maintains the SH-reactive p-nitrophenyl carbamate group, is a FAAH-4 inhibitor .

HY-D0122

6-Iodoacetamidofluorescein	Fluorescent Dye	Others
6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins .

HY-D1869

800CW maleimide	Fluorescent Dye	Others
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .

HY-156377

Biotin-PEG7-Maleimide	Drug-Linker Conjugates for ADC	Cancer
Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .

HY-W440896

DSPE-PEG-SH, MW 2000	Liposome	Others
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.

HY-146691

hMAO-B-IN-2	Monoamine Oxidase	Neurological Disease
hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC₅₀ of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research . hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-113817

SHIP1 activator 1	Others	Inflammation/Immunology
SHIP1 activator 1 is an SH3 domain-containing inositol 5-phosphatase regulator with SHIP1 activating activity. SHIP1 activator 1 retains its SHIA-1 activating ability by removing unnecessary functional groups. SHIP1 activator 1 is able to activate SHIP1 in vitro, inhibit Akt phosphorylation in MOLT-4 cells, and show dose-dependent activity in a mouse model of inflammation. SHIP1 activator 1 is an important chemical tool for evaluating the potential of SHIP1 activators as inhibitors of hematopoietic diseases involving abnormal PI3K cell signaling .

Cat. No.	Product Name	Type

HY-D2381

AF 488 maleimide	Fluorescent Dyes/Probes
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-D0122

6-Iodoacetamidofluorescein	Fluorescent Dyes/Probes
6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins .

HY-D1869

800CW maleimide	Fluorescent Dyes/Probes
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .

Cat. No.	Product Name	Type

HY-W440896

DSPE-PEG-SH, MW 2000	Drug Delivery
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.

HY-W698574

Dansylamidoethyl mercaptan	Indicators
Dansylamidoethyl mercaptan is a molecule that reacts with -SH groups of proteins and other sulfhydryl-containing molecules and has activity for detecting SS bonds in proteins.

Cat. No.	Product Name		Classification

HY-130900

Propargyl-PEG3-SH		PROTAC Synthesis Alkynes
Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-135917

Propargyl-PEG6-SH		PROTAC Synthesis Alkynes
Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130910

Propargyl-PEG8-SH		PROTAC Synthesis Alkynes
Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG8-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130911

Propargyl-PEG12-SH		Alkynes PROTAC Synthesis
Propargyl-PEG12-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG12-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-146691

hMAO-B-IN-2		Alkynes
hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC₅₀ of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research . hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W440896

DSPE-PEG-SH, MW 2000		Pegylated Lipids
DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Name
Email *

	Sorry, but the email address you supplied was invalid.