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SKF-38393

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12520A
    SKF 38393 hydrochloride
    Maximum Cited Publications
    13 Publications Verification

    (±)-SKF-38393 hydrochloride; SKF-38393A

    		 Dopamine Receptor Neurological Disease
    SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
    SKF 38393 hydrochloride
  • HY-12237
    SKF 38393 hydrobromide

    (±)-SKF-38393 hydrobromide

    		 Dopamine Receptor Neurological Disease
    SKF 38393 ((±)-SKF-38393) hydrobromide is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM .
    SKF 38393 hydrobromide
  • HY-12520B
    (R)-SKF 38393 hydrochloride

    (±)-SKF-38393 hydrochloride; SKF-38393A hydrochloride

    		 Dopamine Receptor Potassium Channel Neurological Disease
    (R)-SKF 38393 ((±)-SKF-38393) hydrochloride is a potent and selective D1 dopamine receptor antagonist. (R)-SKF 38393 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channel .
    (R)-SKF 38393 hydrochloride
  • HY-B1752
    Quinpirole

    LY 171555; (-)-LY 141865

    		 Others Neurological Disease
    Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist with activity in reducing hypothalamic norepinephrine concentrations. The effects of Quinpirole are not produced by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity. By activating D2 receptors, Quinpirole leads to a decrease in dopamine metabolites, a decrease in hypothalamic norepinephrine concentrations, and a possible increase in MHPG sulfate by enhancing norepinephrine release .
    Quinpirole

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