2. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  3. Dopamine Receptor Potassium Channel
  4. (R)-SKF 38393 hydrochloride

(R)-SKF 38393 hydrochloride  (Synonyms: (±)-SKF-38393 hydrochloride; SKF-38393A hydrochloride)

Cat. No.: HY-12520B
Handling Instructions

Molarity Calculator

(R)-SKF 38393 ((±)-SKF-38393) hydrochloride is a potent and selective D1 dopamine receptor antagonist. (R)-SKF 38393 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channel.

For research use only. We do not sell to patients.

(R)-SKF 38393 hydrochloride Chemical Structure

(R)-SKF 38393 hydrochloride Chemical Structure

CAS No. : 81702-42-3

Size Price Stock Quantity
1 mg USD 287 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
5 mg USD 717 Get quote 3 - 4 weeks 2 - 3 weeks 2 - 3 weeks
10 mg   Get quote  
50 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (R)-SKF 38393 hydrochloride:

(R)-SKF 38393 hydrochloride Related Antibodies

Top Publications Citing Use of Products

View All Dopamine Receptor Isoform Specific Products:

View All Isoforms
Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(R)-SKF 38393 ((±)-SKF-38393) hydrochloride is a potent and selective D1 dopamine receptor antagonist. (R)-SKF 38393 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channel[1].

In Vitro

(R)-SKF 38393 hydrochloride ((±)-SKF-38393; 0-100 µM) blocks endogenous GIRK currents induced by either somatostatin or D3 dopamine receptors in AtT-20 cells with IC50 value of 268 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(R)-SKF 38393 hydrochloride Related Antibodies
Molecular Weight

291.77

Formula

C16H18ClNO2
CAS No.
SMILES

OC1=C(C=C2[C@H](CNCCC2=C1)C3=CC=CC=C3)O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

(R)-SKF 38393 hydrochloride Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-SKF 3839381702-42-3(±)-SKF-38393SKF-38393ADopamine ReceptorPotassium ChannelKcsApotassium channelAtT-20 cellsGIRKInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(R)-SKF 38393 hydrochloride
Cat. No.:
HY-12520B
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.