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Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist with activity in reducing hypothalamic norepinephrine concentrations. The effects of Quinpirole are not produced by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity. By activating D2 receptors, Quinpirole leads to a decrease in dopamine metabolites, a decrease in hypothalamic norepinephrine concentrations, and a possible increase in MHPG sulfate by enhancing norepinephrine release.

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Quinpirole Chemical Structure

Quinpirole Chemical Structure

CAS No. : 80373-22-4

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Quinpirole Related Antibodies

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Description

Quinpirole (LY 171555) is a dopamine D2/D3 receptor agonist with activity in reducing hypothalamic norepinephrine concentrations. The effects of Quinpirole are not produced by the selective D1 agonist SKF 38393 or the dextrorotatory isomer of Quinpirole, which lacks D2 agonist activity. By activating D2 receptors, Quinpirole leads to a decrease in dopamine metabolites, a decrease in hypothalamic norepinephrine concentrations, and a possible increase in MHPG sulfate by enhancing norepinephrine release[1].

Molecular Weight

219.33

Formula

C13H21N3
CAS No.
SMILES

CCCN1[C@@]2([H])[C@@](CCC1)([H])CC3=C(C=NN3)C2
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Quinpirole Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quinpirole80373-22-4LY 171555 (-)-LY 141865LY171555LY-171555OthersInhibitorinhibitorinhibit

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