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Results for "

Streptonigrin

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124586
    Streptonigrin
    1 Publications Verification

    Bruneomycin

    		 Protein Arginine Deiminase Antibiotic Infection Cancer
    Streptonigrin (Bruneomycin), a natural product produced by Streptomyces flocculus, possesses both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor with IC50s of 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for PAD1, PAD2, PAD3, and PAD4, respectively .
    Streptonigrin
  • HY-123380
    Methyl streptonigrin

    Methyl bruneomycin; NSC-45384

    		 Others Cancer
    Methyl streptonigrin (Methyl bruneomycin) is a derivative of streptonigrin. Methyl streptonigrin has anti-tumor activity .
    Methyl streptonigrin
  • HY-124586A
    (rac)-Streptonigrin

    (rac)-Bruneomycin

    		 Protein Arginine Deiminase Antibiotic Infection Cancer
    (rac)-Streptonigrin ((rac)-Bruneomycin) is the racemic form of Streptonigrin. Streptonigrin (HY-124586) is a natural product produced by the actinobacterium Streptomyces flocculus, exhibiting antitumor and antibacterial activities. Streptonigrin can act as a pan-PAD inhibitor, with IC50 values of 48.3 μM, 26.1 μM, 0.43 μM, and 2.5 μM for PAD1, PAD2, PAD3, and PAD4, respectively .
    (rac)-Streptonigrin
  • HY-137139
    10'-Desmethoxystreptonigrin

    		Antibiotic Bacterial Farnesyl Transferase Infection Cancer
    10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg) .
    10'-Desmethoxystreptonigrin

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